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Abolition of the nerve-induced responses of the isolated vas deferens of the young rat by agents blocking -adrenoceptors.通过阻断β-肾上腺素能受体的药物消除幼鼠离体输精管的神经诱导反应。
Br J Pharmacol. 1972 Jan;44(1):160-1. doi: 10.1111/j.1476-5381.1972.tb07248.x.
2
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Intimacy of the neuroeffector junction and resistance to alpha-adrenoceptor-blockade of the neurogenic contractile response in vasa deferentia from guinea pig and rat.豚鼠和大鼠输精管神经效应器连接的紧密程度以及对神经源性收缩反应的α-肾上腺素能受体阻断的抗性。
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Role of the alpha-receptor in the control of noradrenaline release from sympathetic nerves.α受体在控制交感神经去甲肾上腺素释放中的作用。
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Resistance of mechanical and electrical responses to hypogastric nerve stimulation to alpha-blocking agents in guinea-pig vas deferens.豚鼠输精管中对下腹神经刺激的机械和电反应对α-阻滞剂的抗性。
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本文引用的文献

1
An electrophysiological study of the effects of atropine and physostigmine on transmission to the guinea-pig vas deferens.阿托品和毒扁豆碱对豚鼠输精管传递作用的电生理学研究。
J Physiol. 1967 Mar;189(1):31-42. doi: 10.1113/jphysiol.1967.sp008153.
2
PREGANGLIONIC AND POSTGANGLIONIC STIMULATION OF THE GUINEA-PIG ISOLATED VAS DEFERENS PREPARATION.豚鼠离体输精管标本的节前和节后刺激
Br J Pharmacol Chemother. 1963 Dec;21(3):569-80. doi: 10.1111/j.1476-5381.1963.tb02024.x.
3
The potentiation by anticholinesterase drugs of the responses of the guinea-pig isolated vas deferens to alternate preganglionic and postganglionic stimulation.抗胆碱酯酶药物对豚鼠离体输精管对交替的节前和节后刺激反应的增强作用。
Br J Pharmacol Chemother. 1966 May;27(1):145-56. doi: 10.1111/j.1476-5381.1966.tb01650.x.
4
Biphasic mechanical response of the isolated vas deferens to nerve stimulation.离体输精管对神经刺激的双相机械反应。
Acta Physiol Scand. 1971 Apr;81(4):574-6. doi: 10.1111/j.1748-1716.1971.tb04936.x.

通过阻断β-肾上腺素能受体的药物消除幼鼠离体输精管的神经诱导反应。

Abolition of the nerve-induced responses of the isolated vas deferens of the young rat by agents blocking -adrenoceptors.

作者信息

Swedin G

出版信息

Br J Pharmacol. 1972 Jan;44(1):160-1. doi: 10.1111/j.1476-5381.1972.tb07248.x.

DOI:10.1111/j.1476-5381.1972.tb07248.x
PMID:4401307
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1665677/
Abstract

The mechanical responses of isolated fieldstimulated vasa deferentia from rats 3-10 days old were abolished by low doses of drugs blocking alpha-adrenoceptors. In preparations from older animals this effect was absent or there was a potentiation of the responses. The effect of atropine also changed during postnatal development. In the early period a moderate (10-40%) decline of the nerve-induced responses was generally observed, but later even high concentrations of atropine were without effect.

摘要

低剂量的α-肾上腺素能受体阻断药物可消除3至10日龄大鼠离体场刺激输精管的机械反应。在老年动物的制备物中,这种作用不存在或反应增强。阿托品的作用在出生后发育过程中也发生了变化。在早期,通常观察到神经诱导反应适度(10% - 40%)下降,但后来即使是高浓度的阿托品也没有作用。