[Change in the morphological structure of the population and in the flavin level in the cells of Candida guilliermondii yeasts under periodic cultivation].

The growth of Candida guilliermondii on media with glucose and acetate is described by statistical functions for cell volume (size) distribution. Special instrument has been used to measure the volume of cells and volume distributions. Changes in the morphological structure of populations (both in the average size of cells and in the extent of the size heterogeneity) were detected throughout the whole period of the cultural growth including the exponential phase. These changes hardly differed during the growth on media with glucose or with acetate. The content of flavins in cells also varied in the course of periodic growth. Their total level in cells, as well as the level of FAD, was higher in the exponential phase of growth than during the subsequent phases. Changes in the intracellular level of flavins were found also in yeast populations synchronized by nitrogen limitation.