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钙和镁对小龙虾神经肌肉接头处统计学释放参数的影响。

The effects of calcium and magnesium on statistical release parameters at the crayfish neuromuscular junction.

作者信息

Wernig A

出版信息

J Physiol. 1972 Nov;226(3):761-8. doi: 10.1113/jphysiol.1972.sp010008.

Abstract
  1. Transmitter release at excitatory neuromuscular junctions of crayfish muscle was studied at low temperature by recording synaptic potentials with extracellular micro-electrodes.2. Increasing the Ca concentration in the bathing solution produced an increase in the average number of quanta released per nerve stimulus (m). Increasing the Mg concentration resulted in a decrease in m.3. Statistical analysis of fluctuations in the quantal release from trial to trial, assuming binomial statistics, indicated that both the changes in m were due to changes in the average quantal release probability (p).
摘要
  1. 在低温条件下,通过使用细胞外微电极记录突触电位,研究了小龙虾肌肉兴奋性神经肌肉接头处的递质释放。

  2. 增加浴液中的钙浓度会导致每次神经刺激释放的平均量子数(m)增加。增加镁浓度会导致m降低。

  3. 假设为二项式统计,对每次试验中量子释放波动的统计分析表明,m的变化均归因于平均量子释放概率(p)的变化。

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