Delea C S
Nephron. 1979;23(2-3):91-7. doi: 10.1159/000181615.
Blood pressure in normal and hypertensive subjects shows circadian variability with the minima during the hours of sleep. The factors influencing blood pressure show circadian variability, in particular, plasma and urinary aldosterone, plasma deoxycorticosterone and urinary sodium (factors implicated in cardiac output), angiotensin II as measured by plasma renin activity, plasma and urinary epinephrine and norepinephrine, and plasma and urinary prostaglandins of the E series (factors implicated in peripheral resistance). Direct causal relationships have not been established. The treatment of hypertensive subjects in relation to the circadian variability is reviewed.
正常人和高血压患者的血压呈现昼夜变化，在睡眠期间血压最低。影响血压的因素也呈现昼夜变化，尤其是血浆和尿醛固酮、血浆脱氧皮质酮和尿钠（与心输出量有关的因素）、通过血浆肾素活性测定的血管紧张素II、血浆和尿肾上腺素及去甲肾上腺素，以及E系列的血浆和尿前列腺素（与外周阻力有关的因素）。尚未确立直接的因果关系。本文综述了针对昼夜变化对高血压患者的治疗。
