Levin H S, Rose J E
Neurosurgery. 1979 Feb;4(2):168-74. doi: 10.1227/00006123-197902000-00011.
After a meningioma situated in the trigone of the left lateral ventricle was excised by the transcallosal approach of Kempe and Blaylock, a right-handed musician with a right hemianopsia developed alexia without agraphia. In contrast to previously reported cases of this syndrome arising from other etiologies, he was unable to read single letters or numbers. Neuropsychological studies at 42 and 126 days after operation also disclosed an inability to associate auditory or tactile stimuli with visually perceived material, whereas speech and verbal comprehension were intact. Although the alexia extended to musical notes, he could interpret other musical symbols (e.g., treble clef). Appreciation of rhythm and expressive musical ability were relatively preserved, although judgment of other musical features (including discrimination of pitch, duration, and loudness) was compromised. The findings suggest that alexia may occur as a consequence of the transcallosal procedure when a right hemianopsia is present. However, other linguistic abilities may be better preserved by the transcallosal approach to the ventricle than by a transcortical operation.
一名惯用右手的音乐家患有右侧偏盲，在通过肯普和布莱洛克经胼胝体入路切除位于左侧脑室三角区的脑膜瘤后，出现了失读症但无失写症。与先前报道的由其他病因引起的该综合征病例不同，他无法识别单个字母或数字。术后42天和126天的神经心理学研究还显示，他无法将听觉或触觉刺激与视觉感知的材料联系起来，而语言和言语理解能力完好。尽管失读症扩展到了音符，但他能够解读其他音乐符号（如高音谱号）。虽然对音高、时长和响度等其他音乐特征的判断受到影响，但节奏感知和音乐表达能力相对保留。研究结果表明，当存在右侧偏盲时，经胼胝体手术可能导致失读症。然而，经胼胝体入路处理脑室时，其他语言能力可能比经皮质手术保存得更好。
