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[一名右利手患者的交叉性失读失写症]

[Crossed alexia-agraphia in a right-handed patient].

作者信息

Fournet F, Virat-Brassaud M E, Guard O, Dumas R, Auplat P, Marchal G

出版信息

Rev Neurol (Paris). 1987;143(3):214-9.

PMID:3616368
Abstract

A right-handed man, born of a right-handed family, presented an infarct in the territory of the right middle cerebral artery, with a left hemiplegia, a left lateral homonymous hemianopsia and an expression aphasia. The oral trouble disappeared in some weeks, but later a permanent linguistic deficit persisted, affecting mainly the written language and realizing a clinical picture of alexia-agraphia with Gerstmann's syndrome. The neurolinguistic study showed a preferential alteration of the phonologic system in the written language, and at a lesser degree in the oral modality. The extent of the lesion and the relative integrity of oral expression and comprehension, suggested that these functions were localized in the left hemisphere, whereas lecture, writing, calculation, body-parts notion, laterality notion, had been simultaneously implanted during the ontogenesis in the right hemisphere. The latter was probably also responsible for phonological aspects of written and spoken language, according to a scheme opposite to that of usual right-handers.

摘要

一名右利手男性,出生于右利手家庭,出现右侧大脑中动脉供血区梗死,伴有左侧偏瘫、左侧同向性偏盲和表达性失语。言语问题在数周内消失,但后来持续存在永久性语言缺陷,主要影响书写语言,呈现失读-失写症伴格斯特曼综合征的临床表现。神经语言学研究表明,书写语言中的语音系统有优先改变,口语形式的改变程度较小。病变范围以及口语表达和理解的相对完整性表明,这些功能定位于左半球,而阅读、书写、计算、身体部位概念、左右侧概念在个体发育过程中同时植入了右半球。根据与普通右利手相反的模式,右半球可能也负责书面和口语的语音方面。

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