Perrelli G, Pettinati L
Minerva Med. 1979 Mar 17;70(13):909-18.
The large number of xenobiotic agents, associated with work or otherwise, that can attack the body, and the fundamental part played by the liver in the control of metabolic homeostasis offered the occasion for an examination of the present position with regard to the aetiopathogenesis and diagnosis of occupational toxic diseases of the liver. Attention is particularly directed to recent biochemical knowledge (molecular and cellular), to the main aetiopathogenetic features, and to the most modern criteria for the evaluation of liver damage, especially that of a chronic kind.
大量与工作或其他方面相关的外源性物质会侵袭人体,而肝脏在代谢稳态控制中发挥的关键作用,为审视当前关于职业性肝病的病因发病机制及诊断的现状提供了契机。尤其关注近期的生化知识(分子和细胞层面)、主要病因发病特征以及评估肝损伤,特别是慢性肝损伤的最现代标准。