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既往有传染性单核细胞增多症患者的霍奇金淋巴瘤:30年经验

Hodgkin's disease in patients with previous infectious mononucleosis: 30 years' experience.

作者信息

Rosdahl N, Larsen S O, Clemmesen J

出版信息

Br Med J. 1974 May 4;2(5913):253-6. doi: 10.1136/bmj.2.5913.253.

Abstract

Seventeen out of 17,073 people in Denmark who had had a positive reaction to a Paul-Bunnell test between the years 1940 and 1969 developed Hodgkin's disease after an interval of at least 12 months. This number was significantly (P < 0.0002) greater than the expected number of two women and four men. Sixteen of those developing Hodgkin's disease were men. Case records, which were available for 12 of them, confirmed that they had had infectious mononucleosis. The number of cases of leukaemia that developed in the sample population was no greater than expected.

摘要

1940年至1969年间,丹麦17073名对保罗-邦内尔试验呈阳性反应的人中,有17人在至少间隔12个月后患上了霍奇金病。这个数字显著高于预期的两名女性和四名男性的数量(P<0.0002)。患霍奇金病的16人为男性。其中12人的病历证实他们曾患传染性单核细胞增多症。样本人群中患白血病的病例数不高于预期。

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