Mishaeva N P, Erofeeva N I
Parazitologiia. 1979 May-Jun;13(3):218-22.
The tick encephalitis virus was found to multiply more intensively in ticks developing without diapause. Thus, in larvae developing with diapause, in 4 and 8 weeks after they feed on infected animals, the virus titers were 3.0 and 3.5 lg LD50 respectively. At the development without diapause the titers were 4.3 and 5.3, respectively (P less than 0.05). The virus titers in infected nymphs developing without diapause were 2.5 to 3.9 lg LD50 higher than those of the diapausing individuals. In diapausing larvae and nymphs the tick encephalitis virus remained for a long time (8 to 10 weeks) without fall of titers. The fall of virus titers was not recorded either during the moulting of larvae for nymphs and nymphs for imago but in hungry ticks, which were maintained for a long time at 18 to 23 C, the amount of virus gradually diminished.
发现蜱传脑炎病毒在无滞育发育的蜱中繁殖更为旺盛。因此,在有滞育发育的幼虫中,在以感染动物为食后的4周和8周,病毒滴度分别为3.0和3.5 lg LD50。在无滞育发育时,滴度分别为4.3和5.3(P小于0.05)。无滞育发育的感染若虫中的病毒滴度比滞育个体高2.5至3.9 lg LD50。在滞育的幼虫和若虫中,蜱传脑炎病毒长时间(8至10周)保持滴度不下降。在幼虫变为若虫以及若虫变为成虫的蜕皮过程中均未记录到病毒滴度下降,但在18至23摄氏度下长时间饲养的饥饿蜱中,病毒量逐渐减少。