一种快速、简便的地高辛检测方法。
A rapid, simple assay for digoxin.
作者信息
Greenwood H, Howard M, Landon J
出版信息
J Clin Pathol. 1974 Jun;27(6):490-4. doi: 10.1136/jcp.27.6.490.
Abstract
An extremely rapid radioimmunoassay for digoxin is described which is precise over the range of concentrations required to determine whether, or not, a patient has digoxin toxicity. The assay is based on the use of (125)-iodine-labelled digoxin and of a gel equilibration technique for the separation of antibody-bound and free digoxin. The results obtained compare closely with those by a conventional radioimmunoassay and the technique is sufficiently simple to enable its performance by relatively inexperienced laboratory staff.
摘要
本文描述了一种用于地高辛的超快速放射免疫测定法，该方法在确定患者是否存在地高辛毒性所需的浓度范围内具有精确性。该测定法基于使用（125）碘标记的地高辛以及一种凝胶平衡技术来分离抗体结合型和游离型地高辛。所获得的结果与传统放射免疫测定法的结果非常接近，并且该技术足够简单，使得相对缺乏经验的实验室工作人员也能够进行操作。
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A rapid, simple assay for digoxin.一种快速、简便的地高辛检测方法。
J Clin Pathol. 1974 Jun;27(6):490-4. doi: 10.1136/jcp.27.6.490.
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引用本文的文献
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Relationship between myocardial uptake and actions in heart failure of methyldigoxin.甲地高辛在心力衰竭中的心肌摄取与作用之间的关系。
Br J Clin Pharmacol. 1983 Jan;15(1):41-8. doi: 10.1111/j.1365-2125.1983.tb01461.x.
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Comparison of digoxin and medigoxin in normal subjects.正常受试者中地高辛与甲地高辛的比较。
Br J Clin Pharmacol. 1978 Jul;6(1):81-6. doi: 10.1111/j.1365-2125.1978.tb01686.x.
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[A simplified radioimmunoassay for digoxin determination using a 125-j-labelled, solid-phase kit (author's transl)].[使用125I标记的固相试剂盒简化放射免疫分析法测定地高辛（作者译）]
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Immunoassay of insulin with insulin-antibody precipitate.用胰岛素 - 抗体沉淀物进行胰岛素免疫测定。
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Plasma digoxin concentrations in patients with atrial fibrillation.心房颤动患者的血浆地高辛浓度。
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Measurement of plasma digoxin concentration by radioimmunoassay.用放射免疫分析法测定血浆地高辛浓度。
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Determination of therapeutic and toxic serum digoxin concentrations by radioimmunoassay.采用放射免疫分析法测定治疗性和中毒性血清地高辛浓度。
N Engl J Med. 1969 Nov 27;281(22):1212-6. doi: 10.1056/NEJM196911272812203.
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Coated charcoal immunoassay of insulin.胰岛素的包被炭免疫测定法。
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Serum digoxin by radioimmunoassay.采用放射免疫分析法测定血清地高辛。
Can Med Assoc J. 1971 Jul 24;105(2):170-3.
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Radioimmunoassay for digoxin. Technic and clinical application.
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Improved radioimmunoassay of digoxin and other sterol-like compounds using Somogyi precipitation.使用索莫吉沉淀法改进地高辛及其他类甾醇化合物的放射免疫分析。
J Lab Clin Med. 1972 Nov;80(5):748-54.
10
Radioimmunoassay of plasma digoxin, with use of iodinated tracer.使用碘化示踪剂对血浆地高辛进行放射免疫测定。
Clin Chem. 1973 Feb;19(2):187-90.
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