用放射免疫分析法测定血浆地高辛浓度。
Measurement of plasma digoxin concentration by radioimmunoassay.
作者信息
Evered D C, Chapman C, Hayter C J
出版信息
Br Med J. 1970 Aug 22;3(5720):427-8. doi: 10.1136/bmj.3.5720.427.
Abstract
A rapid, sensitive, and precise method for measuring the plasma digoxin concentration has been developed with the radioimmunoassay technique. Seventy patients receiving digoxin were shown to have plasma digoxin concentrations between 0.4 and 5 ng./ml. Preliminary studies show that though there is a positive correlation between total daily dose and the plasma digoxin concentration, the relationship is not close, and a relatively wide range of plasma digoxin concentrations appear to be consistent with effective digitalization.
摘要
已经采用放射免疫测定技术开发出一种快速、灵敏且精确的测量血浆地高辛浓度的方法。七十名接受地高辛治疗的患者血浆地高辛浓度显示在0.4至5纳克/毫升之间。初步研究表明，尽管每日总剂量与血浆地高辛浓度之间存在正相关，但这种关系并不密切，而且血浆地高辛浓度的相对较宽范围似乎与有效的洋地黄化相一致。
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