β-羟基丁酸、乙酰乙酸和棕榈酸对灌注离体大鼠胰腺胰岛素释放的作用。 - Suppr

Suppr

超能文献

Action of B-hydroxy butyrate, acetoacetate and palmitate on the insulin release in the perfused isolated rat pancreas.

作者信息

Goberna R, Tamarit J, Osorio J, Fussgänger R, Tamarit J, Pfeiffer E F

出版信息

Horm Metab Res. 1974 Jul;6(4):256-60. doi: 10.1055/s-0028-1093862.

DOI:10.1055/s-0028-1093862

PMID:4411830

Abstract

摘要

相似文献

Action of B-hydroxy butyrate, acetoacetate and palmitate on the insulin release in the perfused isolated rat pancreas.β-羟基丁酸、乙酰乙酸和棕榈酸对灌注离体大鼠胰腺胰岛素释放的作用。

Horm Metab Res. 1974 Jul;6(4):256-60. doi: 10.1055/s-0028-1093862.

Effect of beta-hydroxybutyrate and acetoacetate on insulin and glucagon secretion from perfused rat pancreas.β-羟基丁酸和乙酰乙酸对灌注大鼠胰腺胰岛素和胰高血糖素分泌的影响。

Arch Biochem Biophys. 1987 Aug 15;257(1):140-3. doi: 10.1016/0003-9861(87)90552-2.

Stimulation of insulin secretion by noncarbohydrate metabolites.非碳水化合物代谢产物对胰岛素分泌的刺激作用。

J Lab Clin Med. 1968 Sep;72(3):438-48.

The immediate insulin secretory response of the isolated perfused rat pancreas to tolbutamide and glucose.离体灌注大鼠胰腺对甲苯磺丁脲和葡萄糖的即时胰岛素分泌反应。

FEBS Lett. 1975 Jan 1;49(3):407-8. doi: 10.1016/0014-5793(75)80797-6.

Effect of phosphate omission on glucose-induced insulin release in vitro.体外实验中缺磷对葡萄糖诱导的胰岛素释放的影响。

Experientia. 1979 Sep 15;35(9):1260-1. doi: 10.1007/BF01963326.

Relationships between arginine and glucose in the induction of insulin secretion from the isolated, perfused rat pancreas.

Endocrinology. 1972 Mar;90(3):624-31. doi: 10.1210/endo-90-3-624.

The insulinotropic action of gastric inhibitory polypeptide in the perfused isolated rat pancreas.胃抑制性多肽在灌注离体大鼠胰腺中的促胰岛素作用。

Endocrinology. 1976 Sep;99(3):780-5. doi: 10.1210/endo-99-3-780.

Effect of somatostatin on the potentiating action of glucagon, cyclic adenosine monophosphate and theophylline on glucose-induced insulin release.生长抑素对胰高血糖素、环磷酸腺苷及茶碱增强葡萄糖诱导胰岛素释放作用的影响。

Diabete Metab. 1979 Mar;5(1):27-31.

Primary secretion of insulin and secondary release of glucagon from the isolated perfused rat pancreas following stimulation with pancreozymin.用促胰酶素刺激后，分离灌注的大鼠胰腺中胰岛素的原发性分泌和胰高血糖素的继发性释放。

Horm Metab Res. 1969 Jul;1(4):224-7. doi: 10.1055/s-0028-1095139.

Effects of tolbutamide on insulin and glucagon secretion of the isolated perfused rat pancreas.甲苯磺丁脲对离体灌注大鼠胰腺胰岛素和胰高血糖素分泌的影响。

Horm Metab Res. 1971 Jul;3(4):238-42. doi: 10.1055/s-0028-1094161.

引用本文的文献

Ketones and Insulin: A Paradoxical Interplay With Implications for Glucose Metabolism.酮体与胰岛素：对葡萄糖代谢具有影响的矛盾相互作用

J Endocr Soc. 2025 Jun 5;9(8):bvaf101. doi: 10.1210/jendso/bvaf101. eCollection 2025 Aug.

Ingestion of an exogenous ketone monoester improves the glycemic response during oral glucose tolerance test in individuals with impaired glucose tolerance: A cross-over randomized trial.摄入外源性酮单酯可改善糖耐量受损个体口服葡萄糖耐量试验期间的血糖反应：一项交叉随机试验。

J Diabetes Investig. 2021 May;12(5):756-762. doi: 10.1111/jdi.13423. Epub 2020 Nov 1.

Glucose-stimulated insulin response in pregnant sheep following acute suppression of plasma non-esterified fatty acid concentrations.急性抑制血浆非酯化脂肪酸浓度后妊娠绵羊的葡萄糖刺激胰岛素反应。

Reprod Biol Endocrinol. 2004 Sep 7;2:64. doi: 10.1186/1477-7827-2-64.

Palmitate increases L-type Ca2+ currents and the size of the readily releasable granule pool in mouse pancreatic beta-cells.棕榈酸盐可增加小鼠胰腺β细胞中的L型钙离子电流以及易释放颗粒池的大小。

J Physiol. 2004 Jun 15;557(Pt 3):935-48. doi: 10.1113/jphysiol.2004.066258. Epub 2004 Apr 16.

Chronic exposure to free fatty acid reduces pancreatic beta cell insulin content by increasing basal insulin secretion that is not compensated for by a corresponding increase in proinsulin biosynthesis translation.长期暴露于游离脂肪酸会通过增加基础胰岛素分泌来降低胰腺β细胞胰岛素含量，而胰岛素原生物合成翻译并未相应增加以对此进行补偿。

J Clin Invest. 1998 Mar 1;101(5):1094-101. doi: 10.1172/JCI420.

Essentiality of circulating fatty acids for glucose-stimulated insulin secretion in the fasted rat.禁食大鼠中循环脂肪酸对葡萄糖刺激的胰岛素分泌的必要性。

J Clin Invest. 1996 Jun 15;97(12):2728-35. doi: 10.1172/JCI118727.

Opposite effects of short- and long-term fatty acid infusion on insulin secretion in healthy subjects.短期和长期输注脂肪酸对健康受试者胰岛素分泌的相反作用。

Diabetologia. 1995 Nov;38(11):1295-9. doi: 10.1007/BF00401761.

Long-term exposure of rat pancreatic islets to fatty acids inhibits glucose-induced insulin secretion and biosynthesis through a glucose fatty acid cycle.大鼠胰岛长期暴露于脂肪酸会通过葡萄糖脂肪酸循环抑制葡萄糖诱导的胰岛素分泌和生物合成。

J Clin Invest. 1994 Feb;93(2):870-6. doi: 10.1172/JCI117042.

[Regulation of ketone body levels before and following elective surgical operations during different intravenous feedings].[不同静脉喂养方式下择期手术前后酮体水平的调节]

Z Ernahrungswiss. 1982 Sep;21(3):214-24. doi: 10.1007/BF02028814.

Starvation-induced changes of palmitate metabolism and insulin secretion in isolated rat islets stimulated by glucose.饥饿诱导的葡萄糖刺激的离体大鼠胰岛中棕榈酸酯代谢和胰岛素分泌的变化。

Biochem J. 1984 Jul 15;221(2):317-24. doi: 10.1042/bj2210317.

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验