Reich H
Aktuelle Gerontol. 1979 Sep;9(9):411-5.
Aging of the skin appears in circumscribed as well as in generalized forms. The localized alterations may be subdivided in such of inflammatory origin and in hyperplastic ones. The latter include benign and also precancerous tumors. The generalized and usually premature manifestations of cutaneous senescence are almost always part of some hereditary disease which frequently also affects the viscera, sense organs, skeleton, and the nervous system.
皮肤老化表现为局限性和全身性两种形式。局限性改变可细分为炎症性和增生性。后者包括良性肿瘤以及癌前肿瘤。皮肤衰老的全身性且通常为过早出现的表现几乎总是某些遗传性疾病的一部分,这些疾病常常还会影响内脏、感觉器官、骨骼和神经系统。