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Influence of emulsified fat on chlorpromazine availability in rabbit blood.

作者信息

Krieglstein J, Meffert A, Niemeyer D H

出版信息

Experientia. 1974 Aug 15;30(8):924-6. doi: 10.1007/BF01938365.

DOI:10.1007/BF01938365
PMID:4413863
Abstract
摘要

相似文献

1
Influence of emulsified fat on chlorpromazine availability in rabbit blood.乳化脂肪对氯丙嗪在兔血中生物利用度的影响。
Experientia. 1974 Aug 15;30(8):924-6. doi: 10.1007/BF01938365.
2
Influence of dietary lipids on the effect of chlorpromazine on membrane properties of rabbit red cells.膳食脂质对氯丙嗪影响兔红细胞膜特性的作用
Proc R Soc Lond B Biol Sci. 1986 Feb 22;227(1246):43-51. doi: 10.1098/rspb.1986.0008.
3
Plasma disappearance and cerebral effects of chlorpromazine in cirrhosis.肝硬化患者中氯丙嗪的血浆清除率及对脑部的影响
Clin Sci. 1972 Aug;43(2):143-51. doi: 10.1042/cs0430143.
4
Comparison of EEG effects of chlorpromazine, octoclothepin and methiothepin in rabbits.氯丙嗪、辛氧氯平与甲硫噻吨对家兔脑电图影响的比较。
Act Nerv Super (Praha). 1968 Oct 3;10(3):336.
5
Clinical-pharmacological study with the two isomers (d-, l-) of fenfluramine and its comparison with chlorpromazine and d-amphetamine: blood levels, EEG mapping and safety evaluation.芬氟拉明两种异构体（d-、l-）的临床药理学研究及其与氯丙嗪和d-苯丙胺的比较：血药浓度、脑电图地形图及安全性评估。
Methods Find Exp Clin Pharmacol. 1993 Jun;15(5):291-312.
6
The influence of emulsifying agents and of lipid soluble drugs on the fractional removal rate of lipid emulsions from the blood stream of the rabbit.乳化剂和脂溶性药物对兔血流中脂质乳剂分数清除率的影响。
Acta Pharmacol Toxicol (Copenh). 1975 Aug;37(2):134-44. doi: 10.1111/j.1600-0773.1975.tb00830.x.
7
[Comparative study of the effect of chlorpromazine and Ag 246 on cortical and subcortical electrogenesis].[氯丙嗪与Ag 246对皮质及皮质下电发生作用的比较研究]
Agressologie. 1968 Jan-Feb;9(1):137-51.
8
Biochemical and electroencephalographic changes in the brain of rabbits injected with 5-hydroxytryptophan (influence of chlorpromazine premedication).注射5-羟色氨酸的家兔大脑中的生化和脑电图变化（氯丙嗪术前用药的影响）
Am J Physiol. 1958 Jul;194(1):214-20. doi: 10.1152/ajplegacy.1958.194.1.214.
9
Pharmacology of chlorpromazine: clinical studies.氯丙嗪的药理学：临床研究
Br J Pharmacol. 1971 Feb;41(2):431P.
10
[On the influence of megaphen, nembutal and novocain on spontaneous EEG and bioelectrical response to light stimuli in brain-injured rabbits].[关于氯丙嗪、戊巴比妥钠和奴夫卡因对脑损伤家兔自发脑电图及对光刺激的生物电反应的影响]
Dtsch Z Nervenheilkd. 1960;180:450-70.

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Lipid emulsion attenuates vasodilation by decreasing intracellular calcium and nitric oxide in vascular endothelial cells.脂质乳剂通过降低血管内皮细胞内的钙和一氧化氮来减弱血管舒张。
Heliyon. 2024 Sep 3;10(17):e37353. doi: 10.1016/j.heliyon.2024.e37353. eCollection 2024 Sep 15.
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Intravenous lipid emulsion for the treatment of poisonings in 313 dogs and 100 cats (2016-2020).静脉注射脂质乳剂用于治疗313只犬和100只猫的中毒（2016 - 2020年）。
Front Vet Sci. 2023 Sep 28;10:1272705. doi: 10.3389/fvets.2023.1272705. eCollection 2023.
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Lipid Emulsion to Treat Acute Poisonings: Mechanisms of Action, Indications, and Controversies.

本文引用的文献

1
[Quantitative determination of protein binding of drugs by gel filtration].[通过凝胶过滤法定量测定药物的蛋白质结合率]
Arzneimittelforschung. 1968 Mar;18(3):287-9.
2
[Rheological aspects of blood flow in the capillaries in lipemia].[脂血状态下毛细血管内血流的流变学方面]
Klin Wochenschr. 1970 Jun 15;48(12):723-8. doi: 10.1007/BF01497129.
3
[Animal experiments on organ distribution and plasma clearance of labelled lipid emulsions in uremic acidosis].[尿毒症酸中毒时标记脂质乳剂的器官分布及血浆清除率的动物实验]
用于治疗急性中毒的脂质乳剂：作用机制、适应证及争议
Pharmaceutics. 2023 May 3;15(5):1396. doi: 10.3390/pharmaceutics15051396.
4
An 80-Year-Old Woman with Alzheimer Disease and Accidental Poisoning with Pyrethroid Pesticide Successfully Treated with Intravenous Lipid Emulsion.一位 80 岁患有阿尔茨海默病的女性，不慎服用拟除虫菊酯类农药中毒，经静脉用脂肪乳剂成功救治。
Am J Case Rep. 2021 Jun 10;22:e928420. doi: 10.12659/AJCR.928420.
5
Should we consider the infusion of lipid emulsion in the resuscitation of poisoned patients?我们是否应该考虑在中毒患者的复苏过程中输注脂肪乳剂？
Crit Care. 2014 Jul 30;18(5):457. doi: 10.1186/s13054-014-0457-5.
6
Intravenous fat emulsion: a potential novel antidote.静脉脂肪乳剂：一种潜在的新型解毒剂。
J Med Toxicol. 2008 Jun;4(2):109-14. doi: 10.1007/BF03160965.
7
The role of fat emulsion therapy in a rodent model of propranolol toxicity: a preliminary study.脂肪乳剂疗法在普萘洛尔中毒啮齿动物模型中的作用：一项初步研究。
J Med Toxicol. 2006 Mar;2(1):4-7. doi: 10.1007/BF03161005.
8
Disease-induced changes in the plasma binding of basic drugs.疾病引起的碱性药物血浆结合变化。
Clin Pharmacokinet. 1980 May-Jun;5(3):246-62. doi: 10.2165/00003088-198005030-00004.
9
The effect of a lipid suspension on amitriptyline disposition.脂质混悬液对阿米替林处置的影响。
Arch Toxicol. 1987 Aug;60(6):467-9. doi: 10.1007/BF00302392.
10
Methodological aspects of the evaluation of the binding of drugs to plasma and tissue proteins.
Eur J Drug Metab Pharmacokinet. 1979;4(3):123-7. doi: 10.1007/BF03189413.
Arzneimittelforschung. 1972 Jan;22(1):160-2.
4
Complete intravenous nutrition. Theoretical and experimental background.
Nutr Metab. 1972;14:Suppl:1-57.
5
Effect of surfactants on diffusion of drugs across membranes.表面活性剂对药物跨膜扩散的影响。
Nat New Biol. 1972 Mar 15;236(63):44-5. doi: 10.1038/newbio236044a0.
6
The neurotoxic effect of benzylpenicillin and ampicillin studied in the rabbit.苄青霉素和氨苄青霉素对家兔神经毒性作用的研究。
Arzneimittelforschung. 1974 Mar;24(3):317-21.
7
Distribution of chlorpromazine in a simplified blood influenced by various drugs.氯丙嗪在受多种药物影响的简化血液中的分布。
Naunyn Schmiedebergs Arch Pharmacol. 1973;278(1):35-44. doi: 10.1007/BF00501861.
8
[Uptake of promazine, chlorpromazine, and their desmethyl-metabolites into the isolated perfused rat brain].
Naunyn Schmiedebergs Arch Pharmakol. 1971;268(3):300-9.
9
[Significance of the binding of drugs to albumin and erythrocytes in a perfusion medium for the isolated rat liver].[药物与灌注介质中白蛋白及红细胞结合对离体大鼠肝脏的意义]
Naunyn Schmiedebergs Arch Pharmakol. 1971;269(1):67-84.
10
[Comparative study of the plasma epuration kinetics of 2 injectable lipid emulsions in man and in animals].[两种注射用脂质乳剂在人和动物体内血浆清除动力学的比较研究]
C R Seances Soc Biol Fil. 1966;160(6):1234-8.