Dally S, Guillevin B, Maidenberg M, Leclerc J P, Katz M, Gaultier M
Ann Med Interne (Paris). 1979 Dec;130(12):649-52.
The authors describe a case of a drug addict with a hepatitis B who was found to have periarteritis nodosa and a nephrotic syndrome. The course was rapidly fatal and autopsy confirmed the diagnosis. This new case questions the hypothesis suggested of possible toxicity of hard drugs (especially the amphetamines) as being an etiological factor for periarteritis nodosa observed in addicts. Hepatitis B virus, which is involved in the etiology of periarteritis nodosa and some nephrotic syndromes (also reported in addicts) is, in fact, very prevalent in users of hard drugs by the parenteral route.
作者描述了一例患有乙型肝炎的吸毒者,该患者被发现患有结节性多动脉炎和肾病综合征。病程进展迅速,最终导致死亡,尸检证实了诊断结果。这一新病例对下述假说提出了质疑,该假说认为硬性毒品(尤其是苯丙胺类)的潜在毒性可能是导致吸毒者出现结节性多动脉炎的病因。事实上,乙型肝炎病毒参与了结节性多动脉炎和一些肾病综合征(吸毒者中也有报道)的病因,在通过非肠道途径使用硬性毒品的人群中非常普遍。