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慢性肺部疾病患儿支气管分泌物中的蛋白质。I. 与临床诊断的关系。

Proteins in bronchial secretion of children with chronic pulmonary diseases. I. Relation to clinical diagnosis.

作者信息

Gaweł J, Rudnik J, Pryjma J, Zebrak J, Hałuszka J, Rudnik I, Majewska-Zalewska H

出版信息

Scand J Respir Dis. 1979 Apr;60(2):63-8.

PMID:441700
Abstract

Bronchial secretions from 207 children suffering from various pulmonary diseases and from 15 healthy controls were tested concentration of IgA, IgG, lactoferrin and lysozyme. The results obtained suggest that in many cases of chronic lung diseases in children the levels of lactoferrin and immunoglobulins, especially secretory IgA, are very low. In severe infections (cystic fibrosis, bronchiectases) significant increase of IgG concentration was observed.

摘要

对207名患有各种肺部疾病的儿童以及15名健康对照者的支气管分泌物进行了IgA、IgG、乳铁蛋白和溶菌酶浓度检测。所得结果表明,在许多儿童慢性肺部疾病病例中,乳铁蛋白和免疫球蛋白水平,尤其是分泌型IgA水平非常低。在严重感染(囊性纤维化、支气管扩张症)中,观察到IgG浓度显著升高。

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