Hillerdal G, Nõu E
Scand J Respir Dis. 1979 Apr;60(2):76-82.
All patients newly diagnosed as bronchial carcinoma were studied during a 5-year period. There were 212 male and 61 female patients. A careful occupational history was taken and the occupations of the patients in 1950 were compared with the County's official occupational statistics of that year, and their chest X-rays were scrutinized for pleural plaques. A significantly higher proportion of metal workers and workers from the building industry was found among the patients, while agricultural workers were under-represented. Smoking habits did not explain the difference. The number of patients with pleural plaques was four times higher than expected. It is concluded that dust in certain occupations has an additive effect on the carcinogenic effect of smoking.
在5年期间对所有新诊断为支气管癌的患者进行了研究。其中男性患者212例,女性患者61例。详细询问了职业史,并将患者在1950年的职业与当年该县的官方职业统计数据进行了比较,同时仔细检查了他们的胸部X光片以寻找胸膜斑。结果发现,患者中金属工人和建筑工人的比例明显较高,而农业工人的比例则较低。吸烟习惯并不能解释这种差异。胸膜斑患者的数量比预期高出四倍。研究得出结论,某些职业中的粉尘对吸烟的致癌作用具有叠加效应。