恶性疾病中的维生素C缺乏：一项临床与生化研究。
Ascorbic acid deficiency in malignant diseases: a clinical and biochemical study.
作者信息
Krasner N, Dymock I W
出版信息
Br J Cancer. 1974 Aug;30(2):142-5. doi: 10.1038/bjc.1974.125.
Abstract
In a study of the vitamin C status of 50 patients with malignant disease, 46 had leucocyte levels less than the lower limit of the normal range (18-50,μg/10(8) W.B.C.) and of these 30 had very low levels (< 12.5 μg/10(8) W.B.C.). Physical signs compatible with subclinical scurvy were frequently recorded and there was a significant decrease in capillary fragility in those with the lowest levels. Most patients had an inadequate dietary intake of ascorbic acid-containing foods and this was felt to be the major factor in producing the vitamin depletion.
摘要
在一项针对50名恶性疾病患者维生素C状况的研究中，46名患者的白细胞水平低于正常范围下限（18 - 50μg/10⁸白细胞），其中30名患者的白细胞水平极低（< 12.5μg/10⁸白细胞）。经常记录到与亚临床坏血病相符的体征，且白细胞水平最低的患者毛细血管脆性显著降低。大多数患者饮食中抗坏血酸含量丰富的食物摄入不足，这被认为是导致维生素缺乏的主要因素。
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本文引用的文献
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The clinical features of chronic vitamin deficiency. A therapeutic trial in geriatric hospital patients.慢性维生素缺乏的临床特征。老年住院患者的治疗试验。
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