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脐带血浆中凝血的抑制作用(作者译)

[The inhibition of coagulation in cord plasma (author's transl)].

作者信息

Kirchhof B R, Hoheisel M, Keefer L, Hemker H C

出版信息

Z Geburtshilfe Perinatol. 1979 Apr;183(2):163-8.

PMID:442731
Abstract

203 Plasma samples from the umbilical vein were tested for their inhibitory activity in coagulation. Disturbance of the assay by the presence of thrombocytes, fibrin(ogen) degradation products and by storage was avoided by an improved preparation method of the plasma. The mean inhibition was dependent on the way of delivery (spontaneous, by vaginal operation or by caesarean section). The mean inhibition was also dependent on birth weight and on the duration of gravidity. A possible mechanism for the generation of the inhibition is discussed.

摘要

对203份来自脐静脉的血浆样本进行了凝血抑制活性检测。通过改进的血浆制备方法避免了血小板、纤维蛋白(原)降解产物的存在以及储存对检测的干扰。平均抑制作用取决于分娩方式(自然分娩、经阴道手术或剖宫产)。平均抑制作用还取决于出生体重和孕期时长。文中讨论了产生这种抑制作用的可能机制。

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