Goenechea S, Kobbe K, Goebel K J
Z Rechtsmed. 1979 Apr 27;83(1):77-80. doi: 10.1007/BF00201313.
The behaviour of p-nitrophenol and synthetic p-nitrophenol-glucuronide with mineral acids has been investigated. With sulfuric acid (33%) about 93% of the glucuronide derivative have been hydrolysed; the solution was heated in open vessel for 15 sec. With hydrochloric acid (6%) only about 65% of the conjugated p-nitrophenol have been converted to the free form. No losses were detected, when free p-nitrophenol was treated under the same conditions. Three other methods of hydrolysis have been applied.