• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

烧伤脓毒症与烧伤毒素

Burn sepsis and burn toxin.

作者信息

Allgöwer M, Städtler K, Schoenenberger G A

出版信息

Ann R Coll Surg Engl. 1974 Nov;55(5):226-35.

PMID:4429330
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2388479/
Abstract

The salient steps of a 20-year programme of research into the nature of burn disease are described. By burn disease we mean the late mortality and morbidity following burns. We have isolated a burn toxin which is derived from a thermal polymerization of cell membrane lipoproteins within the dermis and have studied its influence on the effects of sepsis. We have also used it in the development of active and passive immunization therapy of severe burns.

摘要

本文描述了一项为期20年的关于烧伤疾病本质的研究的主要步骤。我们所说的烧伤疾病是指烧伤后的晚期死亡率和发病率。我们已经分离出一种烧伤毒素,它源自真皮内细胞膜脂蛋白的热聚合反应,并且研究了其对败血症影响的作用。我们还将其用于重度烧伤的主动和被动免疫治疗的研发中。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/44d7/2388479/be9687d6adbe/annrcse00859-0020-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/44d7/2388479/42e664e833e8/annrcse00859-0016-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/44d7/2388479/d74f620fda6e/annrcse00859-0018-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/44d7/2388479/ce89e7f3c40a/annrcse00859-0019-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/44d7/2388479/4990c713b079/annrcse00859-0019-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/44d7/2388479/06a1b474313b/annrcse00859-0020-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/44d7/2388479/be9687d6adbe/annrcse00859-0020-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/44d7/2388479/42e664e833e8/annrcse00859-0016-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/44d7/2388479/d74f620fda6e/annrcse00859-0018-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/44d7/2388479/ce89e7f3c40a/annrcse00859-0019-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/44d7/2388479/4990c713b079/annrcse00859-0019-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/44d7/2388479/06a1b474313b/annrcse00859-0020-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/44d7/2388479/be9687d6adbe/annrcse00859-0020-b.jpg

相似文献

1
Burn sepsis and burn toxin.烧伤脓毒症与烧伤毒素
Ann R Coll Surg Engl. 1974 Nov;55(5):226-35.
2
[Pathogenetic significance of a specific cutaneous burn toxin for the infection and late mortality following severe burns].[一种特定皮肤烧伤毒素对严重烧伤后感染及晚期死亡率的发病机制意义]
Zentralbl Chir. 1974 Aug 30;99(35):1089-97.
3
Burn toxins isolated from mouse and human skin. Their characterization and immunotherapy effects.从小鼠和人类皮肤中分离出的烧伤毒素。它们的特性及免疫治疗效果。
Monogr Allergy. 1975;9:72-139.
4
[Burn disease--effect of toxin or consequence of infection?].[烧伤疾病——毒素的作用还是感染的后果?]
Chirurg. 1974 Jan;45(1):20-8.
5
Experimental evidence for a significant impairment of host defense for gram-negative organisms by a specific cutaneous toxin produced by severe burn injuries.严重烧伤产生的一种特定皮肤毒素对革兰氏阴性菌宿主防御功能造成显著损害的实验证据。
Surg Gynecol Obstet. 1975 Oct;141(4):555-61.
6
[Pathogenetic and immunotherapeutic significance of a cutaneous burn toxin in experimental pseudomonas infection].[皮肤烧伤毒素在实验性铜绿假单胞菌感染中的发病机制及免疫治疗意义]
Helv Chir Acta. 1974 Mar;41(1-2):7-11.
7
Isolation, activity, and physicochemical characterization of a burn toxin from mouse skin.从小鼠皮肤中分离、鉴定烧伤毒素及其理化特性
Br J Surg. 1969 Sep;56(9):704.
8
Editorial: Burn toxin.社论:烧伤毒素
Lancet. 1974 Dec 14;2(7894):1432-3.
9
[Immunological and immunotherapeutic studies on the model of mice following thermic injury ].[热损伤小鼠模型的免疫学及免疫治疗研究]
Allerg Immunol (Leipz). 1981;27(3):176-87.
10
[Isolation and physical-chemical characterization of a toxic substance produced in mouse skin by thermal energy].
Z Gesamte Exp Med Einschl Exp Chir. 1971;156(2):110-28.

引用本文的文献

1
Unremitting pro-inflammatory T-cell phenotypes, and macrophage activity, following paediatric burn injury.小儿烧伤后持续存在的促炎T细胞表型和巨噬细胞活性。
Clin Transl Immunology. 2024 Mar 8;13(3):e1496. doi: 10.1002/cti2.1496. eCollection 2024.
2
A general overview of burn care.烧伤护理概述。
Int Wound J. 2005 Sep;2(3):206-20. doi: 10.1111/j.1742-4801.2005.00129.x.
3
[Isolated liver cells of the rat under the influence of a toxic factor from burnt human and animal skin (author's transl)].[大鼠离体肝细胞在人及动物烧伤皮肤毒性因子影响下(作者译)]

本文引用的文献

1
Isolation, biological and antigenic properties of a specific toxin formed in thermally altered mouse skin.热变性小鼠皮肤中形成的一种特异性毒素的分离、生物学及抗原特性
Eur J Clin Invest. 1972 Mar;2(3):154-62. doi: 10.1111/j.1365-2362.1972.tb00584.x.
2
Isolation and characterization of a toxic lipid-protein complex formed in mouse skin by controlled thermal energy. Comparison to an inactive precursor derived from thermally unexposed or native skin.通过可控热能在小鼠皮肤中形成的有毒脂质-蛋白质复合物的分离与特性分析。与源自未受热暴露或天然皮肤的无活性前体进行比较。
Biochim Biophys Acta. 1972 Mar 15;263(1):149-63. doi: 10.1016/0005-2795(72)90169-9.
3
Langenbecks Arch Chir. 1980;350(3):151-63. doi: 10.1007/BF01237555.
4
Lung water changes after thermal burns. An observational study.热烧伤后肺水的变化。一项观察性研究。
Ann Surg. 1978 Mar;187(3):288-93. doi: 10.1097/00000658-197803000-00013.
5
Neutrophil chemotaxis in patients with burns.烧伤患者的中性粒细胞趋化作用
Ann Surg. 1977 Dec;186(6):746-8. doi: 10.1097/00000658-197712000-00015.
6
Studies on the structure and biological effects of pyrotoxins purified from burned skin.从烧伤皮肤中纯化的热毒素的结构与生物学效应研究。
World J Surg. 1979 Jul 30;3(3):361-5. doi: 10.1007/BF01556594.
A reduction of Pseudomonas septicemias in burned patients by the immune process.
免疫过程使烧伤患者的假单胞菌败血症减少。
Surg Clin North Am. 1970 Dec;50(6):1377-83. doi: 10.1016/s0039-6109(16)39295-7.