Friman G
Acta Med Scand. 1979;205(5):389-93. doi: 10.1111/j.0954-6820.1979.tb06070.x.
Twenty-two healthy men were confined to bed in a hospital ward (clinical bed rest) for one week. Variables related to physical fitness were measured before and immediately after the bed rest period, as well as one and three months thereafter. As a result of bed rest, maximal oxygen uptake, W170 and total Hb decreased to 94%, and calculated blood volume to 93% of the initial value. Hb concentration and Hct were unaltered. Thus, red cell and plasma volumes were proportionately reduced. No significant orthostatic dysfunction developed. The blood lactate peak at maximum work remained unchanged (14.0 mM/l). The resting exertion of noradrenaline decreased moderately during the bed rest period, whilst that of adrenaline was unchanged. Body weight decreased by a mean of 0.7 kg.
22名健康男性在医院病房内卧床一周（临床卧床休息）。在卧床休息期之前、刚结束时以及之后1个月和3个月测量了与身体素质相关的变量。卧床休息的结果是，最大摄氧量、W170和总血红蛋白降至初始值的94%，计算得出的血容量降至93%。血红蛋白浓度和血细胞比容未改变。因此，红细胞和血浆容量成比例减少。未出现明显的直立性功能障碍。最大运动量时的血乳酸峰值保持不变（14.0毫摩尔/升）。卧床休息期间，去甲肾上腺素的静息分泌适度减少，而肾上腺素的分泌未改变。体重平均下降了0.7千克。
