Persson S G, Ullberg L E
Acta Vet Scand. 1979;20(1):10-5. doi: 10.1186/BF03546624.
The rate of disappearance of Evans blue dye from the blood after an intravenous injection was studied in young foals, between 4 and 105 days of age. This was found to be age dependant, especially during the first month, the initial dye disappearance being much faster than in the adult horse. This would mean an overestimation of plasma volume, using the single sampling technique, of about 5% during the first day of life, i.e. negligible from a practical point of view considering the standard error of estimation. The effect of exercise on the venous haematocrit was studied, too, in foals less than 3 months of age. There was a significant difference between mean values before and after exercise, and this difference seemed to increase with age, indicating an increasing erythrocytestoring capacity of the spleen. This means that even in young foals, the splenic function should be considered when determining the total blood volume from the plasma volume and the venous haematocrit.
对4至105日龄的幼年马驹静脉注射伊文思蓝染料后，研究了其在血液中的消失速率。发现该速率与年龄有关，尤其是在第一个月内，染料最初的消失速度比成年马快得多。这意味着，使用单次采样技术时，出生第一天的血浆量会被高估约5%，即从实际角度考虑，鉴于估计的标准误差，这一高估可忽略不计。还对3个月龄以下马驹运动对静脉血细胞比容的影响进行了研究。运动前后的平均值之间存在显著差异，且这种差异似乎随年龄增加而增大，表明脾脏的红细胞储存能力在增强。这意味着，即使是幼年马驹，在根据血浆量和静脉血细胞比容确定总血容量时，也应考虑脾脏功能。
