Schlippert W, Mitros F, Schulze K
Am J Med. 1979 May;66(5):879-82. doi: 10.1016/0002-9343(79)91146-x.
In a patient with long-staning ulcerative colitis and "backwash" ileitis, multiple carcinomas developed in the colon and ileum. In both locations premalignant mucosal changes of the basal cell proliferation type were seen adjacent to and remote from sites of carcinoma. Although the frequency of such premalignant and malignant changes in "backwash" ileitis is unknown, their concurrence in this case suggests that ulcerative colitis involving the terminal ileum increases the risk of small bowel carcinoma.
在一名患有长期溃疡性结肠炎和“反流性”回肠炎的患者中，结肠和回肠出现了多处癌肿。在癌肿部位附近及远处，均可见到基底细胞增殖型的癌前黏膜改变。虽然“反流性”回肠炎中这种癌前和恶性改变的发生率尚不清楚，但在该病例中的同时出现提示，累及回肠末端的溃疡性结肠炎会增加小肠癌的风险。
