Franks R C, Hayashi R H
Am J Obstet Gynecol. 1979 May 1;134(1):20-2. doi: 10.1016/0002-9378(79)90789-0.
Plasma renin activity (PRA) and the concentrations of renin (PRC) and big renin (PBRC) have been determined in maternal and fetal blood, and renin and big renin have been measured in amniotic fluid, at 16 to 20 weeks of gestation. Gradients between peripheral arterial and venous and uterine venous maternal circulation were not apparent for PRA, PRC, or PBRC. PRC and PBRC but not PRA were consistently higher in fetal cord blood than in the maternal compartment. The concentrations of big renin and of renin were tenfold higher in amniotic fluid than in maternal plasma and were significantly correlated in amniotic fluid but not maternal or fetal plasma.
在妊娠16至20周时，测定了母血和胎儿血中的血浆肾素活性（PRA）、肾素浓度（PRC）和大肾素浓度（PBRC），并测量了羊水中的肾素和大肾素。对于PRA、PRC或PBRC，外周动脉与静脉以及子宫静脉母血循环之间的梯度不明显。胎儿脐血中的PRC和PBRC始终高于母血，而PRA并非如此。羊水中大肾素和肾素的浓度比母血浆高10倍，且在羊水中显著相关，但在母血或胎儿血浆中不相关。
