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急性眼部白血病

Acute ocular leukemia.

作者信息

Kincaid M C, Green W R, Kelley J S

出版信息

Am J Ophthalmol. 1979 May;87(5):698-702. doi: 10.1016/0002-9394(79)90307-6.

DOI:10.1016/0002-9394(79)90307-6
PMID:443342
Abstract

A 71-year-old woman had a history of recent weight loss and bilateral decreased visual acuity, bilateral serous detachment, and mental depression. Fluorescein angiograms showed a myriad of retinal pigment epithelial leakage points. Despite extensive evaluation, the cause of her weight loss and ocular process remained uncertain until her death, when postmortem examination revealed leukemia infiltrates of many organs, including the choroid. After death, we correlated the clinical signs and fluorescein angiograms with the histopathologic findings. This case shows that choroidal disease may be a symptom of undetected leukemia.

摘要

一名71岁女性有近期体重减轻、双侧视力下降、双侧浆液性视网膜脱离及精神抑郁病史。荧光素血管造影显示大量视网膜色素上皮渗漏点。尽管进行了广泛评估,但直至其死亡,其体重减轻和眼部病变的病因仍不明确,尸检发现包括脉络膜在内的多个器官有白血病浸润。死后,我们将临床体征和荧光素血管造影结果与组织病理学发现进行了关联。该病例表明脉络膜疾病可能是未被发现的白血病的一种症状。

相似文献

1
Acute ocular leukemia.急性眼部白血病
Am J Ophthalmol. 1979 May;87(5):698-702. doi: 10.1016/0002-9394(79)90307-6.
2
Central serous choroidopathy with exudative retinal detachment.
Ann Ophthalmol. 1982 Nov;14(11):1035-42.
3
[Uveal effusion syndrome with multiple points of leakage in angiofluorography--Harada's disease?].[血管造影显示多个渗漏点的葡萄膜渗漏综合征——原田病?]
Bull Soc Ophtalmol Fr. 1982 Apr;82(4):627-33.
4
Adult vitelliform macular detachment occurring in patients with basal laminar drusen.
Am J Ophthalmol. 1985 Apr 15;99(4):445-59. doi: 10.1016/0002-9394(85)90012-1.
5
[Bilateral serous detachment of neuroepithelium of the posterior pole disclosing acute leukemia].[双眼后极部神经上皮浆液性脱离提示急性白血病]
J Fr Ophtalmol. 1990;13(11-12):563-8.
6
[Four cases of so-called atypical central serous choroidopathy].
J Fr Ophtalmol. 1983;6(6-7):571-9.
7
Central serous choroidopathy in pregnancy.
Arch Ophthalmol. 1983 Jul;101(7):1055-8. doi: 10.1001/archopht.1983.01040020057010.
8
[Leopard-spot pattern in fluorescein angiography].[荧光素血管造影中的豹斑状图案]
Ophthalmologe. 2013 Apr;110(4):360-4. doi: 10.1007/s00347-012-2771-0.
9
[Choroidal tumor with exsudative retinal detachment?].
Ophthalmologe. 2012 Feb;109(2):161-4. doi: 10.1007/s00347-011-2444-4.
10
PIgment epithelial diseases with abnormal choroidal perfusion.
Am J Ophthalmol. 1980 Nov;90(5):607-18. doi: 10.1016/s0002-9394(14)75127-x.

引用本文的文献

1
Serous retinal detachment as a presenting sign of acute lymphoblastic leukemia: A case report and literature review.浆液性视网膜脱离作为急性淋巴细胞白血病的首发症状:一例报告及文献复习
Am J Ophthalmol Case Rep. 2021 Jun 22;23:101142. doi: 10.1016/j.ajoc.2021.101142. eCollection 2021 Sep.
2
Changes in blood flow velocity and thickness of the choroid in a patient with leukemic retinopathy.白血病性视网膜病变患者脉络膜血流速度和厚度的变化。
Am J Ophthalmol Case Rep. 2018 Sep 6;12:68-72. doi: 10.1016/j.ajoc.2018.09.001. eCollection 2018 Dec.
3
A case of Acute Myeloid Leukemia masquerading as unilateral exudative detachment.
一例伪装成单侧渗出性视网膜脱离的急性髓系白血病病例。
Am J Ophthalmol Case Rep. 2016 Aug 12;4:47-49. doi: 10.1016/j.ajoc.2016.08.004. eCollection 2016 Dec.
4
Enhanced depth imaging optical coherence tomography of precursor cell leukemic choroidopathy before and after chemotherapy.化疗前后前体细胞白血病性脉络膜病变的增强深度成像光学相干断层扫描
Middle East Afr J Ophthalmol. 2015 Apr-Jun;22(2):249-52. doi: 10.4103/0974-9233.150630.
5
Lymphocytic leukemia presenting as acute Vogt-Koyanagi-Harada disease.以急性Vogt-小柳-原田病形式表现的淋巴细胞白血病。
Saudi J Ophthalmol. 2014 Oct;28(4):319-21. doi: 10.1016/j.sjopt.2013.07.013. Epub 2013 Aug 3.
6
Bilateral exudative retinal detachment as a presenting sign of acute lymphoblastic leukemia.双侧渗出性视网膜脱离作为急性淋巴细胞白血病的首发体征
Middle East Afr J Ophthalmol. 2012 Oct;19(4):410-2. doi: 10.4103/0974-9233.102762.
7
Acute lymphoblastic leukemia manifesting as acute Vogt-Koyanagi-Harada disease.表现为急性Vogt-小柳-原田病的急性淋巴细胞白血病
Korean J Ophthalmol. 2009 Dec;23(4):325-8. doi: 10.3341/kjo.2009.23.4.325. Epub 2009 Dec 4.
8
Subretinal hypopyon in prolymphocytic leukaemia.幼淋巴细胞白血病中的视网膜下积脓
Br J Ophthalmol. 1995 Sep;79(9):863-4. doi: 10.1136/bjo.79.9.863.
9
Leukemic optic neuropathy.白血病性视神经病变
Int Ophthalmol. 1981 Mar;3(2):111-6. doi: 10.1007/BF00133423.
10
Recurring bilateral hypopyon in chronic myeloid leukemia in blastic transformation. A case report.慢性粒细胞白血病急变期反复出现双侧前房积脓。一例报告。
Graefes Arch Clin Exp Ophthalmol. 1985;223(4):211-3. doi: 10.1007/BF02174063.