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不同哺乳动物红细胞可变形性的差异。

Variability in erythrocyte deformability among various mammals.

作者信息

Smith J E, Mohandas N, Shohet S B

出版信息

Am J Physiol. 1979 May;236(5):H725-30. doi: 10.1152/ajpheart.1979.236.5.H725.

DOI:10.1152/ajpheart.1979.236.5.H725
PMID:443394
Abstract

Deformability is an important aspect of erythrocyte physiology and has been extensively studied using human red cells. We have studied erythrocytes from 25 different animals using a viscometric technique. Erythrocyte diameters ranged from 3.3 microns in the goat to 11.4 microns for the elephant seal. Erythrocytes from most species deformed readily when a fluid shear stress was applied. A deformability index of the stressed cell defined as (length - width)/(length + width) correlated with cell size. The erythrocytes of four animals (pygmy goat, goat, Batanga horse, and miniature horse) deformed less than most species. Camel and llama erythrocytes, which were ellipsoidal, did not deform but oriented in the stress field.

摘要

可变形性是红细胞生理学的一个重要方面,并且已经使用人类红细胞进行了广泛研究。我们使用粘度测定技术研究了来自25种不同动物的红细胞。红细胞直径范围从山羊的3.3微米到海象的11.4微米。当施加流体剪切应力时,大多数物种的红细胞很容易变形。受压细胞的可变形性指数定义为(长度 - 宽度)/(长度 + 宽度),与细胞大小相关。四种动物(侏儒山羊、山羊、巴坦加马和迷你马)的红细胞变形程度小于大多数物种。骆驼和美洲驼的椭圆形红细胞不会变形,但会在应力场中定向。

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Variability in erythrocyte deformability among various mammals.不同哺乳动物红细胞可变形性的差异。
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