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相似文献

1
Luminal distension as a possible consequence of experimental intestinal perfusion.管腔扩张作为实验性肠灌注的一种可能后果。
Gut. 1974 Sep;15(9):728-32. doi: 10.1136/gut.15.9.728.
2
Perfusion of the hamster jejunum with conjugated and unconjugated bile acids: inhibition of water absorption and effects on morphology.用结合型和非结合型胆汁酸灌注仓鼠空肠：对水吸收的抑制及对形态学的影响。
Gastroenterology. 1972 Feb;62(2):261-7.
3
The effect of conjugated and unconjugated bile acids on water and electrolyte absorption in the human jejunum.结合型和非结合型胆汁酸对人空肠水和电解质吸收的影响。
Clin Sci Mol Med. 1973 Sep;45(3):301-11. doi: 10.1042/cs0450301.
4
Active and passive bile acid absorption in man. Perfusion studies of the ileum and jejunum.人体中胆汁酸的主动和被动吸收。回肠和空肠的灌注研究。
J Clin Invest. 1974 Jun;53(6):1686-94. doi: 10.1172/JCI107720.
5
Effect of deoxycholic, chenodeoxycholic, and cholic acids on intestinal absorption of cholesterol in humans.
Mayo Clin Proc. 1982 Jan;57(1):44-50.
6
Effect of sodium deoxycholate on intestinal glucose absorption and (Na+-K+)-atpase in the rat.脱氧胆酸钠对大鼠肠道葡萄糖吸收及（钠-钾）-ATP酶的影响。
Enzyme. 1980;25(6):387-93. doi: 10.1159/000459287.
7
The effect of glycine-conjugated bile acids on net water and glucose transport, and transmural potential difference, across isolated rat jejunum.
J Physiol. 1973 Feb;229(1):43P-44P.
8
Fat absorption after infusing bile salts into the human small intestine.
Gastroenterology. 1974 Jul;67(1):7-18.
9
Altered jejunal macromolecular barrier induced by alpha-dihydroxy deconjugated bile salts.α-二羟基去结合胆汁盐诱导的空肠大分子屏障改变
Am J Physiol. 1983 Jul;245(1):G122-32. doi: 10.1152/ajpgi.1983.245.1.G122.
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Feeding rats diets containing cheno- or ursodeoxycholic acid or cholestyramine modifies intestinal uptake of glucose and lipids.给大鼠喂食含有鹅去氧胆酸或熊去氧胆酸或消胆胺的日粮会改变肠道对葡萄糖和脂质的摄取。
Digestion. 1987;38(3):160-70. doi: 10.1159/000199586.

本文引用的文献

1
Sodium and water absorption from the human small intestine. The accuracy of the perfusion method.人体小肠对钠和水的吸收。灌注法的准确性。
Gastroenterology. 1966 Dec;51(6):975-84.
2
Occlusion of the jejunum for intestinal perfusion in man.人体空肠阻断用于肠道灌注
Mayo Clin Proc. 1966 Apr;41(4):224-31.
3
Segmental perfusion techniques.节段性灌注技术。
Gastroenterology. 1969 May;56(5):987-9.
4
An evaluation of perfusion techniques in the study of water and electrolyte absorption in man: the problem of endogenous secretions.人体水和电解质吸收研究中灌注技术的评估：内源性分泌物问题
Gut. 1968 Oct;9(5):530-5. doi: 10.1136/gut.9.5.530.
5
Jejunal trauma following perfusion of the small intestine in nontropical sprue.非热带性口炎性腹泻小肠灌注后的空肠创伤
Gastroenterology. 1968 Mar;54(3):417-20.
6
Absorption of glucose, sodium, and water by the human jejunum studied by intestinal perfusion with a proximal occluding balloon and at variable flow rates.通过使用近端阻塞球囊并以不同流速进行肠道灌注研究人体空肠对葡萄糖、钠和水的吸收。
Gut. 1971 Mar;12(3):184-93. doi: 10.1136/gut.12.3.184.
7
Further studies on the perfusion method for measuring intestinal absorption in man: the effects of a proximal occlusive balloon and a mixing segment.关于测量人体肠道吸收的灌注方法的进一步研究：近端阻塞球囊和混合段的影响。
Gut. 1970 Nov;11(11):947-54. doi: 10.1136/gut.11.11.947.
8
A comparison of stable and 14 C-labelled polyethylene glycol as volume indicators in the human jejunum.稳定型与¹⁴C标记的聚乙二醇作为人体空肠容量指标的比较。
Gut. 1972 Oct;13(10):812-5. doi: 10.1136/gut.13.10.812.
9
The effect of conjugated and unconjugated bile acids on water and electrolyte absorption in the human jejunum.结合型和非结合型胆汁酸对人空肠水和电解质吸收的影响。
Clin Sci Mol Med. 1973 Sep;45(3):301-11. doi: 10.1042/cs0450301.
10
Effect of glycine-conjugated bile acids with and without lecithin on water and glucose absorption in perfused human jejunum.含或不含卵磷脂的甘氨酸共轭胆汁酸对灌注人空肠中水和葡萄糖吸收的影响。
J Clin Invest. 1973 May;52(5):1230-6. doi: 10.1172/JCI107290.

管腔扩张作为实验性肠灌注的一种可能后果。

Luminal distension as a possible consequence of experimental intestinal perfusion.

作者信息

Wingate D, Hyams A, Phillips S

出版信息

Gut. 1974 Sep;15(9):728-32. doi: 10.1136/gut.15.9.728.

DOI:10.1136/gut.15.9.728
PMID:4435588
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1413035/
Abstract

In an experimental jejunal perfusion study, distress in healthy subjects occurred during eight out of 16 perfusions in which intestinal secretion was provoked. Calculation demonstrates the volumetric consequences of inadequate recovery of secretory perfusates, and analysis of the perfusion studies shows that distress was significantly associated with poor recovery of the perfusate. These observations are pertinent to increasing interest in the phenomenon of intestinal fluid secretion.

摘要

在一项空肠灌注实验研究中，16次引发肠道分泌的灌注中有8次，健康受试者出现了不适。计算结果显示了分泌性灌注液回收不足所带来的容积后果，对灌注研究的分析表明，不适与灌注液回收不佳显著相关。这些观察结果与人们对肠液分泌现象日益增长的兴趣相关。