Castelló F, Callís L, Nieto J L, Vilaplana E
An Esp Pediatr. 1979 Mar;12(3):207-18.
Fifteen cases of hypervitaminosis D in childhood are reviewed. In all of them, vitamin D was given following medical prescription. In four occasions, excessive dosage of vitamine D impaired the evolution of a previous nephropathy. The clinical, analytical, radiological and histological findings as well as the therapeutical aspects are commented. Hypercalcemia, hypercalciuria, polyuria with hypostenuria, renal failure, bone lesions and nephrocalcinosis are the most prominent features of the picture. Occasionally, arterial hypertension and glycosuria were found. Prednisone, thyrocalcitonine and phosphates were used as therapeutical means. In spite of nephrocalcinosis and renal failure generally present at diagnosis, the clinical course was rather good.
回顾了15例儿童维生素D过多症病例。所有病例中，维生素D均按医嘱给予。有4次，维生素D过量用药影响了先前肾病的病情发展。对临床、分析、放射学和组织学检查结果以及治疗方面进行了评论。高钙血症、高钙尿症、多尿伴低比重尿、肾衰竭、骨病变和肾钙质沉着症是该病症最突出的特征。偶尔还发现有动脉高血压和糖尿。使用泼尼松、降钙素和磷酸盐作为治疗手段。尽管在诊断时通常存在肾钙质沉着症和肾衰竭，但临床病程相当良好。
