Leander J D
Psychopharmacology (Berl). 1979;66(1):19-22. doi: 10.1007/BF00431983.
The effects of propoxyphene, ethoheptazine, and azabicyclane, alone and in combination with 1 mg/kg naloxone, were studied in pigeons responding under a multiple fixed ratio, fixed interval schedule of food presentation. Low doses of pentobarbital (3, 5.6, and 10 mg/kg) attenuated the rate-decreasing effects produced by 20 mg/kg propoxyphene, ethoheptazine, and azabicyclane. Naloxone antagonized the rate-decreasing effects produced by 10 mg/kg azabicyclane but did not antagonize the rate-decreasing effects of propoxyphene or ethoheptazine.
在按多重固定比率、固定间隔食物呈现时间表做出反应的鸽子身上,研究了丙氧芬、乙庚嗪和氮杂双环烷单独使用以及与1毫克/千克纳洛酮联合使用的效果。低剂量戊巴比妥(3、5.6和10毫克/千克)减弱了20毫克/千克丙氧芬、乙庚嗪和氮杂双环烷产生的速率降低效应。纳洛酮拮抗了10毫克/千克氮杂双环烷产生的速率降低效应,但不拮抗丙氧芬或乙庚嗪的速率降低效应。