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[三萜和甾体糖苷的抗菌作用谱]

[Antimicrobial action spectrum of triterpene and steroid glycosides].

作者信息

Shcheglov V V, Baranova S I, Anisimov M M, Antonov A S, Afiiatullov Sh Sh

出版信息

Antibiotiki. 1979 Apr;24(4):270-3.

PMID:443789
Abstract

Antimicrobial activity of 9 triterpene glycosides of the plant and animal origin was studied. It was found that saponins inhibited the fungal growth to different extents and had no activity against grampositive and gramnegative bacteria. Triterpene glycosides of the animal origin, i.e. holoturins A and B, stichoposids A and C had the most pronounced antifungal activity as compared to the saponins isolated from plants. Changes in the length of the carbon chain from 2 to 6 monosugars had no significant effect on the activity of the triterpeneglycosides studied.

摘要

对9种动植物来源的三萜糖苷的抗菌活性进行了研究。发现皂苷对真菌生长有不同程度的抑制作用,对革兰氏阳性菌和革兰氏阴性菌无活性。与从植物中分离得到的皂苷相比,动物来源的三萜糖苷,即海参毒素A和B、刺参皂苷A和C具有最显著的抗真菌活性。碳链长度从2个单糖到6个单糖的变化对所研究的三萜糖苷的活性没有显著影响。

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