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一种用于多发性骨髓瘤尿液电泳的快速技术的临床应用

Clinical application of a rapid technique for urinary electrophoresis in multiple myeloma.

作者信息

Pelletier M, Montplaisir S, Rabin B S

出版信息

Can Med Assoc J. 1974 Dec 21;111(12):1315-7.

Abstract

Proteinuria in three cases of multiple myeloma was studied without prior concentration of the urine, using a simple technique of urinary protein electrophoresis. In each case a free light chain spike was observed in association with a glomerular, tubular or normal urine protein electrophoresis pattem. The suggestion is made that this simple procedure may become a screening test for investigation of renal diseases.

摘要

采用简单的尿蛋白电泳技术,对3例多发性骨髓瘤患者的蛋白尿进行了研究,且未预先浓缩尿液。在每例患者中,均观察到一个游离轻链峰,同时伴有肾小球、肾小管或正常的尿蛋白电泳图谱。有人提出,这一简单程序可能会成为一种用于肾脏疾病研究的筛查试验。

本文引用的文献

1
The characterisation of urine protein by gel filtration.
Clin Chim Acta. 1968 Sep;21(3):357-76. doi: 10.1016/0009-8981(68)90066-1.
3
A rapid technique for the electrophoresis of unconcentrated urine.
Am J Clin Pathol. 1973 Sep;60(3):359-63. doi: 10.1093/ajcp/60.3.359.
5
-Globulin binding of morphine in heroin addicts.
J Lab Clin Med. 1972 Aug;80(2):155-64.

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