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The effect of cerulenin and exogenous fatty acids on triacylglycerol accumulation in an inositol-deficient yeast, Saccharomyces carlsbergensis.

作者信息

Daum G, Gamerith G, Paltauf F

出版信息

Biochim Biophys Acta. 1979 May 25;573(2):413-5. doi: 10.1016/0005-2760(79)90075-4.

Abstract

Cerulenin inhibits fatty acid synthesis in yeast; supplementation with exogenous fatty acids is required to maintain cell growth. In the presence of cerulenin and exogenous fatty acids inositol-deficient cells accumulate triacylglycerols to almost the same extent as normally grown deficient cells, indicating that increased fatty acid synthesis is not primarily responsible for triacylglycerol accumulation.

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