[Effect of intramolecular and intermolecular reactions of the intensity of histone H2A and H4 fluorescence].

Fluorescence of histones H2A and H4 of homo- and hetero-complexes has been studied. It has been found that in the composition of small aggregates consisting of several molecules, the change of histone fluorescence intensity is caused by the change of their tertiary structure. In the composition of large aggregates, including several dozens of molecules, the intramolecular interactions contribute to the change of histone fluorescence. The intermolecular histone interactions are specific and have a cooperative character.