来自老年和年轻人类红细胞的膜糖肽。
Membrane glycopeptides from old and young human erythrocytes.
作者信息
Balduini C, Balduini C L, Ascari E
出版信息
Biochem J. 1974 Jun;140(3):557-60. doi: 10.1042/bj1400557.
Abstract
Glycopeptides were extracted by papain digestion from old and young human erythrocyte membranes and fractionated on DEAE-Sephadex A-25. Chemical characterization of the unfractionated samples and of the main peak eluted from the column indicates that glycoproteins of the erythrocyte membrane undergo significant decreases in sialic acid and galactosamine content with aging.
摘要
通过木瓜蛋白酶消化从老年人和年轻人的红细胞膜中提取糖肽，并在DEAE-葡聚糖A-25上进行分级分离。对未分级样品和从柱上洗脱的主峰进行化学表征表明，红细胞膜糖蛋白的唾液酸和半乳糖胺含量随着年龄增长而显著降低。
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