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1
Self-digestion of human erythrocyte membranes. Role of adenosine triphosphate and glutathione.人红细胞膜的自消化。三磷酸腺苷和谷胱甘肽的作用。
Biochem J. 1977 May 15;164(2):469-72. doi: 10.1042/bj1640469.
2
Identification of a sialoglycopeptide released by self-digestion from human erythrocyte membranes.从人红细胞膜自消化释放的一种唾液酸糖肽的鉴定。
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3
Differential phosphorylation of band 3 and glycophorin in intact and extracted erythrocyte membranes.完整和提取的红细胞膜中带3蛋白和血型糖蛋白的磷酸化差异
J Supramol Struct. 1977;6(1):61-75. doi: 10.1002/jss.400060105.
4
Studies on glutathione transport utilizing inside-out vesicles prepared from human erythrocytes.利用从人红细胞制备的外翻小泡对谷胱甘肽转运的研究。
Biochim Biophys Acta. 1981 Jul 6;645(1):132-6. doi: 10.1016/0005-2736(81)90520-4.
5
[Content of intracellular ATP and structural state of proteins in the erythrocyte membrane].[红细胞膜内ATP含量及蛋白质结构状态]
Biofizika. 1982 May-Jun;27(3):425-9.
6
Diminished spectrin extraction from ATP-depleted human erythrocytes. Evidence relating spectrin to changes in erythrocyte shape and deformability.从ATP耗竭的人红细胞中提取的血影蛋白减少。血影蛋白与红细胞形状和变形性变化相关的证据。
J Clin Invest. 1978 Mar;61(3):815-27. doi: 10.1172/JCI108996.
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[Effect of intracellular ATP on La(3+)-induced aggregation and fusion of human erythrocytes].[细胞内三磷酸腺苷对镧（3+）诱导的人红细胞聚集和融合的影响]
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Effects of lead chloride on human erythrocyte membranes and on kinetic anion sulphate and glutathione concentrations.氯化铅对人红细胞膜及硫酸根和谷胱甘肽阴离子动力学浓度的影响。
Cell Mol Biol Lett. 2012 Dec;17(4):586-97. doi: 10.2478/s11658-012-0027-2. Epub 2012 Sep 1.
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Production and characterization of Escherichia coli enterohemolysin and its effects on the structure of erythrocyte membranes.大肠杆菌肠溶血素的产生、特性及其对红细胞膜结构的影响。
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RLIP76 is the major ATP-dependent transporter of glutathione-conjugates and doxorubicin in human erythrocytes.RLIP76是人类红细胞中谷胱甘肽结合物和阿霉素的主要ATP依赖性转运蛋白。
Arch Biochem Biophys. 2001 Jul 15;391(2):171-9. doi: 10.1006/abbi.2001.2395.

引用本文的文献

1
Inhibition of human polymorphonuclear leukocyte function by 2-cyclohexene-1-one. A role for glutathione in cell activation.2-环己烯-1-酮对人多形核白细胞功能的抑制作用。谷胱甘肽在细胞活化中的作用。
J Clin Invest. 1981 Aug;68(2):535-43. doi: 10.1172/jci110285.
2
Re-evaluation of the structural integrity of red-cell glycoproteins during aging in vivo and nutrient deprivation.体内衰老和营养缺乏过程中红细胞糖蛋白结构完整性的重新评估。
Biochem J. 1987 Feb 15;242(1):115-21. doi: 10.1042/bj2420115.

本文引用的文献

1
Microdetermination of plasma phospholipids by trichloroacetic acid precipitation.用三氯乙酸沉淀法微量测定血浆磷脂
J Lab Clin Med. 1950 Jan;35(1):155-60.
2
Protein measurement with the Folin phenol reagent.使用福林酚试剂进行蛋白质测定。
J Biol Chem. 1951 Nov;193(1):265-75.
3
Chromatography of amino acids on sulfonated polystyrene resins.氨基酸在磺化聚苯乙烯树脂上的色谱分析。
J Biol Chem. 1951 Oct;192(2):663-81.
4
Improved method for the determination of blood glutathione.测定血液中谷胱甘肽的改进方法。
J Lab Clin Med. 1963 May;61:882-8.
5
The contribution of sialic acid to the surface charge of the erythrocyte.唾液酸对红细胞表面电荷的贡献。
J Biol Chem. 1962 Jun;237:1992-2000.
6
Glycoproteins: isolation from cellmembranes with lithium diiodosalicylate.糖蛋白：用二碘水杨酸锂从细胞膜中分离
Science. 1971 Dec 17;174(4015):1247-8. doi: 10.1126/science.174.4015.1247.
7
Analysis of a reversibly polymerizing system by frontal gel filtration. Aggregation of a human erythrocyte membrane glycoprotein.
J Biochem. 1974 Dec;76(6):1183-9. doi: 10.1093/oxfordjournals.jbchem.a130671.
8
Membrane glycopeptides from old and young human erythrocytes.来自老年和年轻人类红细胞的膜糖肽。
Biochem J. 1974 Jun;140(3):557-60. doi: 10.1042/bj1400557.
9
Sialic acid--a determinant of the life-time of rabbit erythrocytes.唾液酸——兔红细胞寿命的一个决定因素。
Hoppe Seylers Z Physiol Chem. 1974 Apr;355(4):395-400. doi: 10.1515/bchm2.1974.355.1.395.
10
Electrophoretic analysis of the major polypeptides of the human erythrocyte membrane.人红细胞膜主要多肽的电泳分析。
Biochemistry. 1971 Jun 22;10(13):2606-17. doi: 10.1021/bi00789a030.

人红细胞膜的自消化。三磷酸腺苷和谷胱甘肽的作用。

Self-digestion of human erythrocyte membranes. Role of adenosine triphosphate and glutathione.

作者信息

Brovelli A, Suhail M, Pallavicini G, Sinigaglia F, Balduini C

出版信息

Biochem J. 1977 May 15;164(2):469-72. doi: 10.1042/bj1640469.

DOI:10.1042/bj1640469
PMID:880253
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1164815/
Abstract

Intact human erythrocytes incubated at 37 degrees C, pH7.4, release a sialoglycopeptide similar in its chemical composition, immunological and aggregation properties to the glycopeptide released by isolated 'ghost' membranes. The presence of ATP or reduced glutathione at physiological concentrations in the incubation medium of 'ghost' membranes inhibits this self-digestion process.

摘要

完整的人类红细胞在37摄氏度、pH值为7.4的条件下孵育，会释放出一种唾液糖肽，其化学组成、免疫和聚集特性与分离的“血影”膜释放的糖肽相似。在“血影”膜的孵育介质中，生理浓度的ATP或还原型谷胱甘肽的存在会抑制这种自我消化过程。