用塞姆利基森林病毒对小鼠脑细胞培养物进行有限感染。
Limited infection of mouse brain cell cultures with Semliki forest virus.
作者信息
Seamer J
出版信息
Br J Exp Pathol. 1974 Dec;55(6):606-14.
Abstract
A simple technique for preparing tissue cultures containing morphologically different types of brain cells from young and adult mice is described. After infection with Semliki forest virus cytopathic effects are slight. The cultures usually support virus multiplication for only a limited period and ultimately no infectious virus can be detected. However, one batch of cultures developed a persistent carrier state of infection.
摘要
本文描述了一种从幼年和成年小鼠制备含有形态不同类型脑细胞的组织培养物的简单技术。用塞姆利基森林病毒感染后，细胞病变效应轻微。这些培养物通常仅在有限的时间段内支持病毒繁殖，最终无法检测到感染性病毒。然而，有一批培养物出现了持续的感染携带状态。
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