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脑死亡的诊断与管理。

Diagnosis and management of brain death.

作者信息

Kaste M, Hillbom M, Palo J

出版信息

Br Med J. 1979 Feb 24;1(6162):525-7. doi: 10.1136/bmj.1.6162.525.

DOI:10.1136/bmj.1.6162.525
PMID:444869
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1598092/
Abstract

Finland was the first country in which brain death was legally accepted. Since 1975, 37 cases of brain death had been recorded in a university hospital in Finland, and these were reviewed. The cause for brain death was intracranial bleeding in 32 cases, other cerebrovascular disorder in two, and intracranial neoplasm in three. In 21 brain death was diagnosed clinically. In 16 cases confirmatory investigations (electroencephalography, cerebral angiography) were needed. After brain death had been established artificial support was withdrawn in 15 patients and organ transplantation was carried out in 10. In 12 patients, however, diagnosis of brain death did not influence management, though the heart stopped beating on average 25 hours after diagnosis. The Finnish criteria for brain death seem to be reliable and suitable for routine use.

摘要

芬兰是首个在法律上接受脑死亡的国家。自1975年以来,芬兰一家大学医院记录了37例脑死亡病例,并对这些病例进行了回顾。脑死亡的原因是颅内出血32例,其他脑血管疾病2例,颅内肿瘤3例。21例脑死亡是临床诊断的。16例需要进行确诊检查(脑电图、脑血管造影)。脑死亡确诊后,15例患者停止了人工支持,10例进行了器官移植。然而,在12例患者中,脑死亡的诊断并未影响治疗,尽管平均在诊断后25小时心脏停止跳动。芬兰的脑死亡标准似乎可靠且适合常规使用。

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Taking the pulse of brain death: A meta-analysis of the natural history of brain death with somatic support.脑死亡的脉搏:支持躯体的脑死亡自然史的荟萃分析。
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Identification of potential organ donors after aneurysmal subarachnoid hemorrhage in a population-based neurointensive care in Eastern Finland.在芬兰东部的一个基于人群的神经重症监护病房中对动脉瘤性蛛网膜下腔出血后的潜在器官捐献者进行鉴定。
Acta Neurochir (Wien). 2018 Aug;160(8):1507-1514. doi: 10.1007/s00701-018-3600-2. Epub 2018 Jun 27.
3
An appalling Panorama.
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ABC of brain stem death. Prognostic significance of a dead brain stem.脑干死亡基础。脑干死亡的预后意义。
Br Med J (Clin Res Ed). 1983 Jan 8;286(6359):123-4. doi: 10.1136/bmj.286.6359.123.

本文引用的文献

1
After the "definition of irreversible coma".在“不可逆昏迷的定义”之后。
N Engl J Med. 1969 Nov 6;281(19):1070-1. doi: 10.1056/NEJM196911062811909.
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[Brain death. Summary of a symposium].[脑死亡。一场研讨会的总结]
Lakartidningen. 1972 Aug 16;69(34):3804-14.
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Irrecoverable brain damage after resuscitation: brain death and other syndromes.复苏后不可恢复的脑损伤:脑死亡及其他综合征
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