地高辛的药代动力学：人体二室模型与三室模型的比较 - Suppr

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Pharmacokinetics of digoxin: comparison of a two- and a three-compartment model in man.

作者信息

Kramer W G, Lewis R P, Cobb T C, Forester W F, Visconti J A, Wanke L A, Boxenbaum H G, Reuning R H

出版信息

J Pharmacokinet Biopharm. 1974 Aug;2(4):299-312. doi: 10.1007/BF01061404.

DOI:10.1007/BF01061404

PMID:4449007

Abstract

摘要

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Pharmacokinetics of digoxin: comparison of a two- and a three-compartment model in man.地高辛的药代动力学：人体二室模型与三室模型的比较

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Rate and extent of drug accumulation after multiple dosing revisited.多次给药后药物蓄积的速度和程度再探讨。

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本文引用的文献

THE METABOLISM OF DIGOXIN IN NORMAL SUBJECTS.正常受试者体内地高辛的代谢

J Pharmacol Exp Ther. 1964 Aug;145:203-9.

Administration of tritiated digoxin with and without a loading dose. A metabolic study.给予和不给予负荷剂量的氚标记地高辛。一项代谢研究。

Circulation. 1966 Nov;34(5):865-74. doi: 10.1161/01.cir.34.5.865.

Localization of the renal excretion of the tritiated digoxin.氚标记地高辛经肾脏排泄的定位

Am J Med Sci. 1969 Sep;258(3):181-9. doi: 10.1097/00000441-196909000-00005.

Some pharmacokinetic aspects of 5-(dimethylriazeno)-imidazole-4-carboxamide in the dog.5-（二甲基三氮烯基）-咪唑-4-甲酰胺在犬体内的一些药代动力学方面

J Pharm Sci. 1968 Dec;57(12):2126-31. doi: 10.1002/jps.2600571221.

Determination of therapeutic and toxic serum digoxin concentrations by radioimmunoassay.采用放射免疫分析法测定治疗性和中毒性血清地高辛浓度。

N Engl J Med. 1969 Nov 27;281(22):1212-6. doi: 10.1056/NEJM196911272812203.

General treatment of linear mammillary models with elimination from any compartment as used in pharmacokinetics.线性乳突模型的一般处理方法，即如药代动力学中所使用的那样，从任何隔室中消除。

J Pharm Sci. 1972 Apr;61(4):536-41. doi: 10.1002/jps.2600610408.

The specificity of the digoxin radioimmunoassay procedure.地高辛放射免疫分析方法的特异性。

Res Commun Chem Pathol Pharmacol. 1972 Nov;4(3):503-10.

Role of pharmacokinetics in drug dosage adjustment. I. Pharmacologic effect kinetics and apparent volume of distribution of digoxin.药代动力学在药物剂量调整中的作用。I. 地高辛的药理效应动力学及表观分布容积。

J Clin Pharmacol New Drugs. 1973 Apr;13(4):127-41. doi: 10.1002/j.1552-4604.1973.tb00074.x.

Statistical estimations in pharmacokinetics.药物动力学中的统计学估计

J Pharmacokinet Biopharm. 1974 Apr;2(2):123-48. doi: 10.1007/BF01061504.

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