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Pharmacokinetics of digoxin: comparison of a two- and a three-compartment model in man.

作者信息

Kramer W G, Lewis R P, Cobb T C, Forester W F, Visconti J A, Wanke L A, Boxenbaum H G, Reuning R H

出版信息

J Pharmacokinet Biopharm. 1974 Aug;2(4):299-312. doi: 10.1007/BF01061404.

DOI:10.1007/BF01061404

PMID:4449007

Abstract

摘要

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本文引用的文献

THE METABOLISM OF DIGOXIN IN NORMAL SUBJECTS.

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Administration of tritiated digoxin with and without a loading dose. A metabolic study.

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Some pharmacokinetic aspects of 5-(dimethylriazeno)-imidazole-4-carboxamide in the dog.

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Determination of therapeutic and toxic serum digoxin concentrations by radioimmunoassay.

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General treatment of linear mammillary models with elimination from any compartment as used in pharmacokinetics.

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The specificity of the digoxin radioimmunoassay procedure.

Res Commun Chem Pathol Pharmacol. 1972 Nov;4(3):503-10.

Role of pharmacokinetics in drug dosage adjustment. I. Pharmacologic effect kinetics and apparent volume of distribution of digoxin.

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