Harris J L, Krueger T R, Parer J T
Gynecol Obstet Invest. 1979;10(6):306-10. doi: 10.1159/000299982.
Parasympathetic and beta-adrenergic blocking agents were administered to near term chronically instrumented sheep. Parasympathetic blockade resulted in a significant increase in fetal heart rate and fetal arterial blood pressure, with a minimal nonsignificant increase in umbilical blood flow. beta-Adrenergic blockade resulted in a decrease in fetal heart rate and umbilical blood flow, though neither was statistically significant. There was no change in arterial blood pressure. The net result of parasympathetic and beta-adrenergic blockade on fetal heart rate suggests that the intrinsic rate is the same as when these influences are present.
对接近足月且长期植入仪器的绵羊给予副交感神经和β-肾上腺素能阻滞剂。副交感神经阻滞导致胎儿心率和胎儿动脉血压显著升高，脐血流量有轻微但无统计学意义的增加。β-肾上腺素能阻滞导致胎儿心率和脐血流量下降，尽管两者均无统计学意义。动脉血压无变化。副交感神经和β-肾上腺素能阻滞对胎儿心率的最终结果表明，内在心率与存在这些影响时相同。
