Anah C O
Am J Trop Med Hyg. 1974 Sep;23(5):930-4. doi: 10.4269/ajtmh.1974.23.930.
Conservative management of 11 consecutive cases of tetanus with diazepam in heavy doses and methocarbamol is described. All drugs were administered intravenously through a cut-down. Patients were nursed near the nurses' station for the first 3 to 5 days when fatal complications and very severe spasms are most likely to occur. There was minimal interference with the patients and a reasonable reduction in the duration of significant spasms, and complications were minimized. No neonates were included. Severity of tetanus cannot be determined only by consideration of onset of symptoms before admission. It is suggested that a combination of muscle relaxants without heavy sedation may produce an improvement in the results of conservative management of clinical tetanus.
描述了连续11例破伤风患者采用大剂量地西泮和甲氯芬酯进行保守治疗的情况。所有药物均通过切开静脉进行静脉注射。在最有可能发生致命并发症和非常严重痉挛的最初3至5天,患者在护士站附近接受护理。对患者的干扰最小,显著痉挛的持续时间得到合理缩短,并发症也降至最低。未纳入新生儿。破伤风的严重程度不能仅通过考虑入院前症状的发作来确定。建议在不进行深度镇静的情况下联合使用肌肉松弛剂可能会改善临床破伤风保守治疗的效果。