两性霉素B联合利福平对粗球孢子菌菌株的体外抑制作用。
In vitro inhibition of Coccidioides immitis strains with amphotericin B plus rifampin.
作者信息
Rifkind D, Crowder E D, Hyland R N
出版信息
Antimicrob Agents Chemother. 1974 Dec;6(6):783-4. doi: 10.1128/AAC.6.6.783.
Abstract
Rifampin was shown in vitro to decrease the amphotericin B minimal inhibitory concentrations of all of 10 strains of Coccidioides immitis tested. These decreases ranged from two- to fourfold and occurred with rifampin concentrations of 10 to 40 mug/ml. Rifampin alone was without effect.
摘要
体外实验表明，利福平可降低所测试的10株粗球孢子菌的两性霉素B最低抑菌浓度。这些降低幅度在两倍至四倍之间，且在利福平浓度为10至40微克/毫升时出现。单独使用利福平则无效果。
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