Soliman M H
Genetics. 1974 Nov;78(3):897-904. doi: 10.1093/genetics/78.3.897.
Lines previously selected for different speed of development were found to differ in their spontaneous and induced wing abnormalities after single exposure to X-ray (10 KR) in Tribolium castaneum at 33 degrees and 70% relative humidity. At the time of irradiation the mean developmental time (from egg to first day pupa) was 16.9, 18.8, 22.8 and 18.4 days for fast, intermediate, slow and unselected lines, respectively. There was no difference between males and females in their responses. The spontaneous rate (angular values) of wing abnormalities was 5.3%, 11.2%, 3.5% and 7.2%, and the corresponding induced values were 16.7%, 20.5%, 11.7% and 25.2% for fast, intermediate, slow and unselected lines, respectively. The difference between the spontaneous (due to selection) and the induced (due to selection and irradiation) rates indicates that slowing down development will probably increase the efficiency of the repair of the irradiation damage. This difference (angular values) was 11.4%, 9.4% and 8.1% for fast, intermediate and slow lines, respectively. Increasing developmental time by one day resulted in repairing 0.56% of the radiation damage. These results indicate that both the genetic and the developmental state of the line influence both induction and repair of the X-irradiation damage. The relationship between development, cell cycle, protein synthesis and repair is discussed.
在33摄氏度和70%相对湿度条件下，对赤拟谷盗进行单次X射线（10千伦琴）照射后，先前因发育速度不同而选择的品系在自发和诱导的翅异常方面存在差异。在辐照时，快速、中间、缓慢和未选择品系从卵到化蛹第一天的平均发育时间分别为16.9天、18.8天、22.8天和18.4天。雄性和雌性的反应没有差异。快速、中间、缓慢和未选择品系翅异常的自发率（角度值）分别为5.3%、11.2%、3.5%和7.2%，相应的诱导率分别为16.7%、20.5%、11.7%和25.2%。自发（由于选择）率和诱导（由于选择和辐照）率之间的差异表明，发育速度减慢可能会提高辐照损伤的修复效率。快速、中间和缓慢品系的这种差异（角度值）分别为11.4%、9.4%和8.1%。发育时间每增加一天，可修复0.56%的辐射损伤。这些结果表明，品系的遗传和发育状态都会影响X射线辐照损伤的诱导和修复。文中还讨论了发育、细胞周期、蛋白质合成与修复之间的关系。
