Varcoe R, Haliday D, Tavill A S
Gut. 1974 Nov;15(11):898-902. doi: 10.1136/gut.15.11.898.
A study of urea and albumin metabolism was carried out in a patient with the stagnant loop syndrome and in a control subject using radioisotopic and stable isotopic techniques. The patient had a higher rate of urea synthesis, urea hydrolysis in the gut, and of incorporation of recycled urea nitrogen into albumin. Although only a small proportion (0.4%) of the urea nitrogen available was used for albumin synthesis and this constituted only 0.8% of the daily nitrogen requirement for this purpose, the reutilization of nitrogen was relatively much greater than was observed in the control study.
采用放射性同位素和稳定同位素技术,对一名患有肠袢淤滞综合征的患者和一名对照受试者进行了尿素和白蛋白代谢研究。该患者的尿素合成率、肠道尿素水解率以及循环尿素氮掺入白蛋白的比率均较高。尽管可利用的尿素氮中只有一小部分(0.4%)用于白蛋白合成,且这仅占该目的每日氮需求量的0.8%,但氮的再利用相对而言比对照研究中观察到的要大得多。