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贝叶斯定理在定量临床化学检测结果中的应用。

Application of Bayes's theorem to results of quantitative clinical chemical determinations.

作者信息

van der Helm H J, Hische E A

出版信息

Clin Chem. 1979 Jun;25(6):985-8.

PMID:445835
Abstract

The diagnostic implication of a certain test result with regard to a certain condition can be expressed as a single number, L, the likelihood ratio of this result. This ratio allows Bayes's theorem to be written in a convenient form. We show that the practice of calculating predictive values for the results of quantitative tests by use of discrimination limits leads to incorrect predictive values. Including L values in laboratory reports seems a more logical approach to optimum interpretation of laboratory results than the use of discrimination values.

摘要

某一检测结果对于某一病症的诊断意义可用一个单一数字L来表示,即该结果的似然比。这个比值能让贝叶斯定理以一种便捷的形式呈现。我们发现,利用判别限来计算定量检测结果的预测值的做法会得出错误的预测值。相较于使用判别值,在实验室报告中纳入L值似乎是对实验室结果进行最佳解读的更合理方法。

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