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Microsomal synthesis of cholesterol from squalene, Lanosterol, and desmosterol. Evidence for the presence of two noncatalytic activator proteins in the 105,000 g supernatant fraction from brain, heart, and kidney.

作者信息

Johnson R C, Shah S N

出版信息

Arch Biochem Biophys. 1974 Oct;164(2):502-10. doi: 10.1016/0003-9861(74)90060-5.

DOI:10.1016/0003-9861(74)90060-5
PMID:4460877
Abstract
摘要

相似文献

1
Microsomal synthesis of cholesterol from squalene, Lanosterol, and desmosterol. Evidence for the presence of two noncatalytic activator proteins in the 105,000 g supernatant fraction from brain, heart, and kidney.
Arch Biochem Biophys. 1974 Oct;164(2):502-10. doi: 10.1016/0003-9861(74)90060-5.
2
Binding of squalene, lanosterol, desmosterol, and cholesterol to proteins in brain and liver 105,000 g supernatant fractions: evidence for specific binding sites.角鲨烯、羊毛甾醇、去氢胆甾醇和胆固醇与脑和肝脏105,000g上清液组分中蛋白质的结合:特异性结合位点的证据。
Lipids. 1976 Sep;11(9):645-51. doi: 10.1007/BF02532881.
3
Evidence for the participation of two soluble noncatalytic proteins in hepatic microsomal cholesterol synthesis.两种可溶性非催化蛋白参与肝脏微粒体胆固醇合成的证据。
Biochem Biophys Res Commun. 1973 Jul 2;53(1):105-11. doi: 10.1016/0006-291x(73)91407-1.
4
Cholesterol biosynthesis in polychlorinated biphenyl-treated rats.
Environ Res. 1982 Feb;27(1):10-5. doi: 10.1016/0013-9351(82)90052-4.
5
Incorporation of 14C acetate into the sterols of rabbit lens in organ culture.在器官培养中14C醋酸盐掺入兔晶状体的甾醇中。
Curr Eye Res. 1982;2(9):607-11. doi: 10.3109/02713688208996361.
6
The binding of squalene by human placental cytosol: role in conversion of squalene to lanosterol.
FEBS Lett. 1974 Oct 1;47(1):66-71. doi: 10.1016/0014-5793(74)80427-8.
7
Enzyme inhibition during the conversion of squalene to cholesterol.角鲨烯转化为胆固醇过程中的酶抑制作用。
Steroids. 1995 Jul;60(7):475-83. doi: 10.1016/0039-128x(95)00054-t.
8
Sterol content and squaline-2(3)-epoxide-lanosterol cyclase activity in human foetal brain during early and mid-gestation.妊娠早期和中期人胎儿大脑中的甾醇含量及鲨烯-2(3)-环氧-羊毛甾醇环化酶活性
J Neurochem. 1974 Jun;22(6):1019-25. doi: 10.1111/j.1471-4159.1974.tb04331.x.
9
Purification and properties of sterol carrier protein1.固醇载体蛋白1的纯化及特性
J Biol Chem. 1976 Sep 25;251(18):5496-504.
10
Effects of a supernatant protein activator on microsomal squalene-2,3-oxide-lanosterol cyclase.上清液蛋白激活剂对微粒体角鲨烯-2,3-环氧化物-羊毛甾醇环化酶的影响。
J Biol Chem. 1979 Dec 10;254(23):11816-21.

引用本文的文献

1
Regulation of bile-acid synthesis. Role of sterol carrier protein 2 in the biosynthesis of 7 alpha-hydroxycholesterol.胆汁酸合成的调节。固醇载体蛋白2在7α-羟基胆固醇生物合成中的作用。
Biochem J. 1985 Aug 15;230(1):19-24. doi: 10.1042/bj2300019.
2
Binding of squalene, lanosterol, desmosterol, and cholesterol to proteins in brain and liver 105,000 g supernatant fractions: evidence for specific binding sites.角鲨烯、羊毛甾醇、去氢胆甾醇和胆固醇与脑和肝脏105,000g上清液组分中蛋白质的结合:特异性结合位点的证据。
Lipids. 1976 Sep;11(9):645-51. doi: 10.1007/BF02532881.