M蛋白在吞噬作用中的作用。II. 化脓性链球菌的体外调理作用。
The role of M protein in phagocytosis. II. Opsonization of Streptococcus pyogenes in vitro.
作者信息
Tylewska S, Hryniewicz W
出版信息
Zentralbl Bakteriol Orig A. 1979 Oct;245(1-2):44-7.
PMID:44622
Abstract
Opsonization of two different streptococcal group A type 12 strains was investigated. The strains differed only in M protein presence. It was observed that after the treatment of bacteria with fresh normal rabbit serum M positive strains bind to their surface IgG only whereas M negative strains solely some complement components. These results may suggest that streptococci lacking M protein are able to activate complement by alternate pathway.
摘要
对两种不同的A群12型链球菌菌株的调理作用进行了研究。这些菌株仅在M蛋白的存在方面有所不同。观察到，在用新鲜的正常兔血清处理细菌后，M阳性菌株仅在其表面结合IgG，而M阴性菌株仅结合一些补体成分。这些结果可能表明，缺乏M蛋白的链球菌能够通过替代途径激活补体。
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