多形核白细胞对化脓性链球菌的趋化活性。
Chemotactic activity of polymorphonuclear leukocytes to Streptococcus pyogenes.
作者信息
Tylewska S, Kłosińska-Kita E, Malinowski W
出版信息
Zentralbl Bakteriol Orig A. 1978 Sep;241(3):294-300.
PMID:364883
Abstract
Influence of two different streptococcal group A type 12 strains on chemotactic activity of polymorphonuclear leukocytes (PMN) was investigated in vitro and in vivo. The strains differed only in presence of M protein. In both conditions, the inhibition of the chemotaxis of the PMN after their treatment with M positive strains was observed. These results suggest that M protein of streptococci inhibits chemotaxis of PMN and therefore they can weaken defensive mechanisms of infected organism.
摘要
在体外和体内研究了两种不同的A组12型链球菌菌株对多形核白细胞（PMN）趋化活性的影响。这两种菌株仅在M蛋白的存在上有所不同。在两种情况下，均观察到用M阳性菌株处理后的PMN趋化性受到抑制。这些结果表明，链球菌的M蛋白抑制PMN的趋化性，因此它们会削弱受感染机体的防御机制。
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