Scheele J, von der Emde J, Shanahan R J
Chirurg. 1979 Mar;50(3):151-7.
Pulmonary embolectomy is the most effective form of treatment in acute, massive pulmonary embolism. Persistent cardio-respiratory failure, in spite of intensive medical therapy, presents a clear indication for embolectomy. A relative indication is given with the occlusion of more than 50% of the pulmonary arterial tree, especially in the case of beginning circulatory failure and contraindications to fibrinolytic therapy. Preoperative angiography is essential and should be performed whenever possible. A dramatic deterioration of the patient's condition may, however, require a prior reestablishment of sufficient circulation with relief of the right ventricle. According to the clarity of symptoms, either immediate thoracotomy or peripheral canulation and partial cardio-pulmonary bypass with subsequent angiography on the operating table should be preferred. Even a long resuscitation with persistently dilated, non-reactive pupils does not exclude operative success, and justifies neither the ommission nor the premature discontinuance of a resolute and consistent therapy.
肺栓子切除术是治疗急性大面积肺栓塞最有效的方法。尽管进行了强化药物治疗,但持续的心肺功能衰竭是肺栓子切除术的明确指征。相对指征是肺动脉树阻塞超过50%,尤其是在出现循环衰竭且有纤维蛋白溶解疗法禁忌证的情况下。术前血管造影至关重要,应尽可能进行。然而,患者病情急剧恶化可能需要先恢复足够的循环并缓解右心室压力。根据症状的明确程度,应优先选择立即开胸手术或外周插管并进行部分体外循环,随后在手术台上进行血管造影。即使经过长时间复苏,瞳孔持续散大且无反应,也不排除手术成功的可能,也不能成为省略或过早停止果断和持续治疗的理由。