Rothmund M, Prieto J L, Kümmerle F
Dtsch Med Wochenschr. 1979 May 4;104(18):653-9. doi: 10.1055/s-0028-1103961.
Experience gained from 100 patients with surgically and histologically proven primary hyperparathyroidism over a period of 14 years led to simplification of diagnostic procedures and development of a surgical scheme. Over the years patients with discrete disease symptoms or with asymptomatic disease were observed more frequently. This can be seen as the result of earlier diagnosis due to increasing spread of laboratory autoanalysers and the resulting routine calcium determination. Development of surgical intervention is characterised by omitting preoperative diagnostic procedures to determine localisation, a schematised operation, and more reliance on macroscopic criteria rather than on quick sections during surgery.
在14年期间，对100例经手术和组织学证实的原发性甲状旁腺功能亢进患者的经验促使诊断程序简化并形成了一种手术方案。多年来，出现离散疾病症状或无症状疾病的患者更为常见。这可以看作是由于实验室自动分析仪的日益普及以及由此导致的常规钙测定，从而实现了早期诊断的结果。手术干预的发展特点是省去术前确定定位的诊断程序、采用程式化手术，并且在手术过程中更多地依赖宏观标准而非快速切片。
